Academic Journal
Microbiota Gut-Brain Axis and Neurodegenerative Disease: A systematic review on Alzheimer’s disease, Amyotrophic lateral sclerosis and Parkinson Disease
| العنوان: | Microbiota Gut-Brain Axis and Neurodegenerative Disease: A systematic review on Alzheimer’s disease, Amyotrophic lateral sclerosis and Parkinson Disease |
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| المؤلفون: | Oluwatobi, Poluyi Edward, Ese, Imaguezegie Grace, Oluwatumininu, Poluyi Abigail, Eghosa, Morgan |
| المصدر: | Romanian Neurosurgery; Vol. XXXIV, No. 1 (March 2020); 116-122 ; 2344-4959 ; 1220-8841 |
| بيانات النشر: | London Academic Publishing |
| سنة النشر: | 2020 |
| المجموعة: | London Academic Publishing Ltd.: Arts & Humanities Journals |
| مصطلحات موضوعية: | gut dysbiosis, central nervous system, gastrointestinal tract, enteric nervous system, neuroimmune system, neuroendocrine system, autonomic nervous system (ANS) |
| الوصف: | This review highlights the microbiota gut-brain axis and neurodegenerative diseases excluding studies on animal models. Gut microbiota is capable of modulating some brain activities via the microbiota gut-brain axis. A bidirectional communication exists between the gastrointestinal (GI) tract and the central nervous system (CNS) in the microbiota gut-brain axis. Gut dysbiosis has been linked to neurodegenerative diseases as a result of the imbalance in the composition of its microbiota, which has a damaging effect on the host’s health. The association between the role and mechanism of CNS disease and gut microbial is yet to be fully explored. Although some studies have shown a positive relationship between a rich diverse microbial community and the brain of the host, and a negative relationship between microbial dysbiosis, intestinal infection and human brain health, our knowledge, however, is limited due to the inability to identify the major players in this heterogeneous microbial community. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | https://journals.lapub.co.uk/index.php/roneurosurgery/article/view/1350/1172; https://journals.lapub.co.uk/index.php/roneurosurgery/article/view/1350 |
| DOI: | 10.33962/roneuro-2020-016 |
| الاتاحة: | https://journals.lapub.co.uk/index.php/roneurosurgery/article/view/1350 https://doi.org/10.33962/roneuro-2020-016 |
| رقم الانضمام: | edsbas.D6DFCF6A |
| قاعدة البيانات: | BASE |
| DOI: | 10.33962/roneuro-2020-016 |
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