Academic Journal
COVID-19: A Recommendation to Examine the Effect of Mouthrinses with β-Cyclodextrin Combined with Citrox in Preventing Infection and Progression
| العنوان: | COVID-19: A Recommendation to Examine the Effect of Mouthrinses with β-Cyclodextrin Combined with Citrox in Preventing Infection and Progression |
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| المؤلفون: | Carrouel, Florence, Conte, Maria, Fisher, Julian, Gonçalves, Lucio, Souza, Dussart, Claude, Llodra, Juan, Bourgeois, Denis |
| المساهمون: | Parcours santé systémique (P2S), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Centro Interdipartimentale Galvani (CIG), Alma Mater Studiorum Università di Bologna = University of Bologna (UNIBO), Central Pharmacy Lyon, Hospices Civils de Lyon (HCL), Universidad de Granada = University of Granada (UGR) |
| المصدر: | ISSN: 2077-0383 ; Journal of Clinical Medicine ; https://univ-lyon1.hal.science/hal-02545367 ; Journal of Clinical Medicine, 2020, 2020, ⟨10.3390/jcm9041126⟩. |
| بيانات النشر: | HAL CCSD MDPI |
| سنة النشر: | 2020 |
| المجموعة: | HAL Lyon 1 (University Claude Bernard Lyon 1) |
| مصطلحات موضوعية: | COVID-19, 2019-nCoV, SARS-CoV-2, oral cavity, mouthrinse, β-cyclodextrins, Citrox, viral load, microbiome, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases |
| الوصف: | International audience ; Considered to be a major portal of entry for infectious agents, the oral cavity is directly associated with the evolutionary process of SARS-CoV-2 in its inhalation of ambient particles in the air and in expectorations. Some new generations of mouth rinses currently on the market have ingredients that could contribute to lower the SARS-CoV-2 viral load, and thus facilitate the fight against oral transmission. If chlorhexidine, a usual component of mouth rinse, is not efficient to kill SARS-CoV-2, the use of a mouth rinses and/or with local nasal applications that contain β-cyclodextrins combined with flavonoids agents, such as Citrox, could provide valuable adjunctive treatment to reduce the viral load of saliva and nasopharyngeal microbiota, including potential SARS-CoV-2 carriage. We urge national agencies and authorities to start clinical trials to evaluate the preventive effects of βCD-Citrox therapeutic oral biofilm rinses in reducing the viral load of the infection and possibly disease progression. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | hal-02545367; https://univ-lyon1.hal.science/hal-02545367; https://univ-lyon1.hal.science/hal-02545367/document; https://univ-lyon1.hal.science/hal-02545367/file/Carrouel%20et%20al%20%28jcm%29%202020.pdf |
| DOI: | 10.3390/jcm9041126 |
| الاتاحة: | https://univ-lyon1.hal.science/hal-02545367 https://univ-lyon1.hal.science/hal-02545367/document https://univ-lyon1.hal.science/hal-02545367/file/Carrouel%20et%20al%20%28jcm%29%202020.pdf https://doi.org/10.3390/jcm9041126 |
| Rights: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.D6DA3854 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/jcm9041126 |
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