Dynamic changes in LANA-NB morphology after lytic induction.

التفاصيل البيبلوغرافية
العنوان: Dynamic changes in LANA-NB morphology after lytic induction.
المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)
سنة النشر: 2021
المجموعة: Smithsonian Institution: Digital Repository
مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.
الوصف: A . iSLK RFP-LANA cells untreated or induced by Dox or Dox+NaB for 24 h, or JQ1for 32 h were assayed by IF for RFP-LANA (red) and DAPI (blue). Scale bar = 10 μm. B . KSHV DNA FISH (green) combined with RFP-LANA IF (red) and DAPI (blue) in iSLK RFP-LANA cells untreated (top) or induced with Dox+NaB for 24h (lower panels). Scale bar = 10 μm. White arrows indicate examples of LANA ring-like structures.
نوع الوثيقة: still image
اللغة: unknown
Relation: https://figshare.com/articles/figure/Dynamic_changes_in_LANA-NB_morphology_after_lytic_induction_/13618744
DOI: 10.1371/journal.ppat.1009231.g005
الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.g005
Rights: CC BY 4.0
رقم الانضمام: edsbas.D53B6D01
قاعدة البيانات: BASE
الوصف
DOI:10.1371/journal.ppat.1009231.g005