Academic Journal
Role of Drug-Induced Sleep Endoscopy in the Diagnosis of Obstructive Sleep Apnoea Syndrome: A Clinical Study
| العنوان: | Role of Drug-Induced Sleep Endoscopy in the Diagnosis of Obstructive Sleep Apnoea Syndrome: A Clinical Study |
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| المؤلفون: | Satish Kale, Daripally Venkatesh, Sarath Kumar Alam |
| المصدر: | International Journal of Pharmaceutical and Clinical Research, 16(1), 1752-1758, (2024-01-30) |
| بيانات النشر: | International Journal of Pharmaceutical and Clinical Research |
| سنة النشر: | 2024 |
| المجموعة: | Zenodo |
| مصطلحات موضوعية: | Drug-Induced Sleep Endoscopy (DISE), Obstructive Sleep Apnoea (OSA), Snoring |
| الوصف: | Background: Obstructive Sleep Apnea (OSA) involves recurrent partial or complete upper airway blockage during sleep, causing airflow reduction. This leads to frequent hypoxia, carbon dioxide buildup, and arousals to restore airway patency, disrupting sleep. Diagnosing OSA relies on clinical history, polysomnography, and drug-induced sleep endoscopy (DISE). This study aims to assess the anesthetist’s role in DISE, addressing the limited existing data on this aspect. Methods: This study included 30 patients with a history of snoring and night arousals selected for Drug-Induced sleep endoscopy (DISE) after taking informed consent. Inj. propofol 0.5mg/kg wt loading dose, followed by 200mcg/kg/min infusion given throughout the procedure, and upper airway nasal endoscopy performed to see the site of airway obstruction. Lowest SpO 2 apnoeic episodes, total propofol used, and DISE findings were recorded. The airway was managed after the procedure till the subject regained consciousness. Results: In this study, BMI distribution revealed 16.67% of cases with normal BMI, 63.33% in the overweight category, and 20% with BMI >30 kg/m². SpO 2 ranged from 82.40% to 94.00%, with a mean fall of 81.40 ± 8.92%. Apneic episodes were assessed in 30 individuals with Obstructive Sleep Apnea, with 60% reporting no episodes. Age-wise analysis showed mean apneic episodes and SpO 2 variations. The mean dose of injection propofol was 1.52 ± 0.16 mg/Kg, varying across age groups. The comparison of the values aged between age, BMI, SpO 2 , and total propofol dose requirement observed that there were significant correlations between age and low SpO 2 (p=0.001), BMI and low SpO 2 (P=0.0001), and BMI and inj. Propofol requirement (P=0.001). Conclusion: Drug-induced sleep Endoscopy (DISE) is a dynamic, safe, and easy-to-perform technique that visualizes the anatomical sites of snoring or apneas and guides the design of a tailor-made treatment plan in individual cases. Lower readings of SpO 2 have been observed in patients with ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | https://doi.org/10.5281/zenodo.11131040; https://doi.org/10.5281/zenodo.11131041; oai:zenodo.org:11131041; https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue1,Article288.pdf |
| DOI: | 10.5281/zenodo.11131041 |
| الاتاحة: | https://doi.org/10.5281/zenodo.11131041 https://impactfactor.org/PDF/IJPCR/16/IJPCR,Vol16,Issue1,Article288.pdf |
| Rights: | info:eu-repo/semantics/openAccess ; Creative Commons Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/legalcode |
| رقم الانضمام: | edsbas.D480BF62 |
| قاعدة البيانات: | BASE |
| DOI: | 10.5281/zenodo.11131041 |
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