التفاصيل البيبلوغرافية
| العنوان: |
Pemphigus vulgaris antigen, a desmoglein type of cadherin, is localized within keratinocyte desmosomes |
| المؤلفون: |
Masayuki Amagai, Ronald Prussick, Kerstin Cehrs, John R. Stanley |
| المساهمون: |
The Pennsylvania State University CiteSeerX Archives |
| المصدر: |
ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/82/4b/J_Cell_Biol_1993_Jul_2_122(2)_409-415.tar.gz |
| سنة النشر: |
1993 |
| المجموعة: |
CiteSeerX |
| الوصف: |
Pemphigus vulgaris antigen (PVA) is a member of the desmoglein subfamily of cadherin cell adhesion molecules. Because autoantibodies in this disease cause blisters due to loss of epidermal cell adhesion, and because desmoglein is found in the desmosome cell adhesion junction, we wanted to determine if PVA is also found in desmosomes. By immunofluorescence, PV IgG bound, in a dotted pattern, to the cell surface of cultured human keratinocytes induced to differentiate with calcium, suggesting junctional staining. However, by preembedding, immunogold electron microscopic studies only slight labeling could be detected in desmosomes, presumably because of difficulty in gold penetration of intact desmosomes. We therefore treated the keratinocytes with |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/zip |
| اللغة: |
English |
| Relation: |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.274.602 |
| الاتاحة: |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.274.602 |
| Rights: |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: |
edsbas.D4004070 |
| قاعدة البيانات: |
BASE |