Academic Journal

The methodology of developing dermato-cosmetic remedies for prevention and treatment of alopecia ; Методология создания дерматокосметических средств для профилактики и лечения алопеции ; Методологія створення дерматокосметичних засобів для профілактики та лікування алопеції

التفاصيل البيبلوغرافية
العنوان: The methodology of developing dermato-cosmetic remedies for prevention and treatment of alopecia ; Методология создания дерматокосметических средств для профилактики и лечения алопеции ; Методологія створення дерматокосметичних засобів для профілактики та лікування алопеції
المؤلفون: Fedorovska, M. I., Polovko, N. P., Yarema, I. O.
المصدر: Clinical pharmacy; Vol. 22 No. 1 (2018); 20-27 ; Клиническая фармация; Том 22 № 1 (2018); 20-27 ; Клінічна фармація; Том 22 № 1 (2018); 20-27 ; 2518-1572 ; 1562-725X
بيانات النشر: National University of Pharmacy
سنة النشر: 2018
المجموعة: Clinical Pharmacy (E-Journal) / Клінічна фармація
مصطلحات موضوعية: alopecia, dermato-cosmetic remedies, methodology, technology, UDC 615.263, 616.594.14, алопеция, дерматокосметические средства, методология, технология, УДК 615.263, алопеція, дерматокосметичні засоби, методологія, технологія
Time: 616-08
الوصف: Prevention and treatment of alopecia remains an important task of modern dermatology and cosmetology. There are different types of baldness depending on the etiology and pathogenetic factors, among them androgenic alopecia (AA)and telogen effluvium (TE) are the most common.Aim. To substantiate the methodology of developing new dermatological remedies intended for the cutaneous application in prevention and treatment of AA and TA.Materials and methods. The study was conducted by processing the research literature in etiology, pathogenesis and applied therapeutic methods of various types of alopecia, marketing analysis of drugs and cosmetics, the search of themedicinal plant raw material, determination of the effect of biologically active substances on recovery and the hair follicle growth stimulation.Results. Taking into account the specificity of pharmacotherapy of alopecia and the marketing research data the study objects were selected, namely for AA treatment – soft dosage forms (emulsion gel, cream-mask, gel-mask) with Saw Palmetto fruits extract and Sophora japonica tincture, an oil extract from nettle rhizomes and roots; for TA treatment – a gel-mask with nettle juice, a complex tincture of nettle leaves, sage leaves and horse chestnut leaves. In order to provide stability, high efficiency and safety it is important to take into account the impact of pharmaceutical factors on the quality of drugs to be developed using modern research methods (pharmacotechnological, biopharmaceutical, physicochemical, pharmacological) and the sequence of their performance.Conclusions. Thus, based on the general methodological approach the algorithm for developing dermato-cosmetic remedies with the natural raw material has been worked out, in future these remedies can be the medicines of choice in prevention and treatment of AA and TA. ; Профилактика и лечение алопеции остаются актуальной задачей современной дерматокосметологии. В зависимости от этиопатогенетических факторов различают разные виды облысения, среди которых ...
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: Ukrainian
Relation: http://cphj.nuph.edu.ua/article/view/cphj.18.1450/120964; http://cphj.nuph.edu.ua/article/view/cphj.18.1450
DOI: 10.24959/cphj.18.1450
الاتاحة: http://cphj.nuph.edu.ua/article/view/cphj.18.1450
https://doi.org/10.24959/cphj.18.1450
Rights: Copyright (c) 2018 National University of Pharmacy ; https://creativecommons.org/licenses/by/4.0
رقم الانضمام: edsbas.D334513
قاعدة البيانات: BASE