Academic Journal

Results of wearing test with two different latex gloves with and without the use of skin‐protection cream

التفاصيل البيبلوغرافية
العنوان: Results of wearing test with two different latex gloves with and without the use of skin‐protection cream
المؤلفون: Baur, X., Chen, Z., Allmers, H., Raulf‐Heimsoth, M.
المصدر: Allergy ; volume 53, issue 4, page 441-443 ; ISSN 0105-4538 1398-9995
بيانات النشر: Wiley
سنة النشر: 1998
المجموعة: Wiley Online Library (Open Access Articles via Crossref)
الوصف: A total of 109 subjects reporting symptoms indicating type I hypersensitivity reactions to natural rubber latex (NRL) gloves was included in this study, and 66 of them had latex‐specific IgE antibodies. They underwent provocation tests by wearing two types of NRL gloves with high (n=103) and low ( n =75) allergen contents. The first glove type caused positive skin reactions in 30% of IgE‐positive and in 3% of IgE‐negative subjects. After application of a commercially available skin protection (barrier) cream, the frequencies of positive skin responses in wearing tests increased to 41% and 7%, respectively. The gloves with low allergen content did not cause hypersensitivity without skin‐protection cream but induced responses in 5% of IgE‐positive subjects when this cream was applied. Corresponding findings were obtained in intraindividual comparisons of test results, which were possible in 69 cases. Of all wearing‐test responders. 92% had latex‐specific IgE antibodies. Our results demonstrate that high allergen contents in latex gloves frequently elicite skin responses in NRL‐sensitized subjects, and that skin‐protection creams may favor the uptake of allergens from gloves, thus increasing allergic reactions. The stipulation of a legally binding threshold limit value (TLV) for allergens in NRL products is urgently needed. This TLV should not be set above 2 ng allergen/g rubber.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1111/j.1398-9995.1998.tb03920.x
الاتاحة: http://dx.doi.org/10.1111/j.1398-9995.1998.tb03920.x
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https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1398-9995.1998.tb03920.x
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رقم الانضمام: edsbas.D24734FD
قاعدة البيانات: BASE
الوصف
DOI:10.1111/j.1398-9995.1998.tb03920.x