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Mesenchymal stromal cells: cell-based therapies for traumatic central nervous system injuries

التفاصيل البيبلوغرافية
العنوان: Mesenchymal stromal cells: cell-based therapies for traumatic central nervous system injuries
المؤلفون: Takeo Mukai, Kenshi Sei, Tokiko Nagamura-Inoue
المصدر: Journal of Integrative Neuroscience, Vol 21, Iss 2, p 044 (2022)
بيانات النشر: IMR Press
سنة النشر: 2022
المجموعة: Directory of Open Access Journals: DOAJ Articles
مصطلحات موضوعية: mesenchymal stromal cell, traumatic central nervous system injury, neurological disorders, umbilical cord, neurotrophic factors, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
الوصف: Traumatic central nervous system (CNS) injury often causes irreversible impairment, and new alternative therapies for the treatment of CNS injury and sequelae are expected to be developed. Recently, mesenchymal stromal cells (MSCs) have started being used as cell therapy for neurological disorders such as traumatic CNS injury based on their immunomodulatory, neuroprotective, and neurorestorative abilities. Based on the premise of basic research, numerous clinical trials using MSCs for the treatment of traumatic CNS injury have been performed, and the feasibility and efficacy of this therapy have been reported. In this review we aimed to shed light on the characteristics of MSCs and to discuss the basic and clinical research and recent progress in clinical studies using MSCs to treat various traumatic neurological injuries.
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 0219-6352
Relation: https://www.imrpress.com/journal/JIN/21/2/10.31083/j.jin2102044; https://doaj.org/toc/0219-6352; https://doaj.org/article/8fefce6a79bd424489a4055f89562475
DOI: 10.31083/j.jin2102044
الاتاحة: https://doi.org/10.31083/j.jin2102044
https://doaj.org/article/8fefce6a79bd424489a4055f89562475
رقم الانضمام: edsbas.D2414064
قاعدة البيانات: BASE
الوصف
تدمد:02196352
DOI:10.31083/j.jin2102044