التفاصيل البيبلوغرافية
| العنوان: |
Data_Sheet_1_Acute Changes in Carotid-Femoral Pulse-Wave Velocity Are Tracked by Heart-Femoral Pulse-Wave Velocity.pdf |
| المؤلفون: |
Keeron Stone (9921080), Simon Fryer (9921086), James Faulkner (3744767), Michelle L. Meyer (6407693), Gabriel Zieff (10006838), Craig Paterson (10006841), Kathryn Burnet (10002201), Elizabeth Kelsch (10002199), Daniel Credeur (10006844), Danielle Lambrick (4421188), Lee Stoner (4446283) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Cardiology, Cardiology (incl. Cardiovascular Diseases), Cardiorespiratory Medicine and Haematology not elsewhere classified, arterial stiffness, measurement, vascular risk, Doppler ultrasound, pulse-transit time |
| الوصف: |
Background: Carotid-femoral pulse-wave velocity (cfPWV) is the reference standard measure of central arterial stiffness. However, it requires assessment of the carotid artery, which is technically challenging, and subject-level factors, including carotid artery plaque, may confound measurements. A promising alternative that overcomes these limitations is heart-femoral PWV (hfPWV), but it is not known to what extent changes in cfPWV and hfPWV are associated. Objectives: To determine, (1) the strength of the association between hfPWV and cfPWV; and (2) whether change in hfPWV is associated with change in cfPWV when central arterial stiffness is perturbed. Methods: Twenty young, healthy adults [24.0 (SD: 3.1) years, 45% female] were recruited. hfPWV and cfPWV were determined using Doppler ultrasound at baseline and following a mechanical perturbation in arterial stiffness (120 mmHg thigh occlusion). Agreement between the two measurements was determined using mixed-effects regression models and Bland-Altman analysis. Results: There was, (1) strong (ICC > 0.7) agreement between hfPWV and cfPWV (ICC = 0.82, 95%CI: 0.69, 0.90), and, (2) very strong (ICC > 0.9) agreement between change in hfPWV and cfPWV (ICC = 0.92, 95%CI: 0.86, 0.96). cfPWV was significantly greater than hfPWV at baseline and during thigh occlusion (both P < 0.001). Inspection of the Bland-Altman plot, comparing cfPWV and corrected hfPWV, revealed no measurement magnitude bias. Discussion: The current findings indicate that hfPWV and cfPWV are strongly associated, and that change in cfPWV is very strongly associated with change in hfPWV. hfPWV may be a simple alternative to cfPWV in the identification of cardiovascular risk in clinical and epidemiological settings. |
| نوع الوثيقة: |
dataset |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/dataset/Data_Sheet_1_Acute_Changes_in_Carotid-Femoral_Pulse-Wave_Velocity_Are_Tracked_by_Heart-Femoral_Pulse-Wave_Velocity_pdf/13612055 |
| DOI: |
10.3389/fcvm.2020.592834.s001 |
| الاتاحة: |
https://doi.org/10.3389/fcvm.2020.592834.s001 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.D1D59A37 |
| قاعدة البيانات: |
BASE |