Academic Journal
Retreatment rates and postprocedural complications are higher than expected after BPH surgeries: a US healthcare claims and utilization study
| العنوان: | Retreatment rates and postprocedural complications are higher than expected after BPH surgeries: a US healthcare claims and utilization study |
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| المؤلفون: | Kaplan, Steve, Kaufman, Ronald P., Mueller, Thomas, Elterman, Dean, Chughtai, Bilal, Rukstalis, Daniel, Woo, Henry, Roehrborn, Claus |
| المصدر: | Prostate Cancer and Prostatic Diseases ; ISSN 1365-7852 1476-5608 |
| بيانات النشر: | Springer Science and Business Media LLC |
| سنة النشر: | 2023 |
| الوصف: | Background Up to 50% of men over 50 and 80% over 80 are affected by BPH. Shared decision-making regarding BPH treatment options can benefit from an improved understanding of relative risks and benefits for various treatments. Methods Data for this longitudinal retrospective population-based cohort study were obtained from a random sample of US Medicare and commercial claims (IBM Watson MarketScan) and restricted to men undergoing BPH surgery (TURP, PVP, PUL, WVTT) from 2015 to 2021 across all sites of service. Retreatments included Holmium laser enucleation and index procedures. Main outcomes were rates of retreatment and procedural complications over 1 year, identified via CPT and ICD-9/10CM codes. Procedural complications that occurred at least 1 day post-index treatment were assessed, as were surgical retreatments with patients who had at least 1 and 5 year’s-worth of data. Baseline phenotype characterization did not control for symptomatology and was limited to age, comorbidities, and BMI. Univariate cumulative incidence estimates, cumulative proportion and log-rank tests justified inclusion for covariate (e.g., age, comorbidities) adjustment in Cox proportional hazard models. Results 43,147 men diagnosed with BPH underwent 22,629 TURP, 11,392 PVP, 7,529 PUL, and 1,597 WVTT. At 1-year post-index: PUL was associated with the lowest rate of complication (PUL 15%, TURP 17%; PVP 19%, ; WVTT 26%); retreatment rates were not different (TURP 5.3%, PVP 5.3%, PUL 5.9%, WVTT 6.2%). At 5 years post-index: retreatment was lowest for TURP (7.0%) and was not significantly different between PVP and PUL (8.9% and 11.6%, respectively). Conclusions Real-world patients diagnosed with BPH may be selected to undergo one of the various available therapies based on patient preference or baseline phenotype. These therapies, however, are associated with different risks for complications. The results of this study suggest that within one year of BPH surgery, one-in-twenty patients may require retreatment regardless of ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1038/s41391-023-00741-8 |
| الاتاحة: | http://dx.doi.org/10.1038/s41391-023-00741-8 https://www.nature.com/articles/s41391-023-00741-8.pdf https://www.nature.com/articles/s41391-023-00741-8 |
| Rights: | https://creativecommons.org/licenses/by/4.0 ; https://creativecommons.org/licenses/by/4.0 |
| رقم الانضمام: | edsbas.D1A7AFA2 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1038/s41391-023-00741-8 |
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