التفاصيل البيبلوغرافية
| العنوان: |
Ligation of left anterior descending coronary artery. Surgical technique |
| المؤلفون: |
Olivares R., Gabriel, Moran V., Sergio, Palacios M., Cristian, Apablaza E., Felipe, Godoy J., Ivan, Zalaquett S., Ricardo, Paz Ocaranza J., Maria |
| بيانات النشر: |
SOC CIRUJANOS CHILE |
| سنة النشر: |
2024 |
| المجموعة: |
Pontificia Universidad Católica de Chile: Repositorio UC |
| مصطلحات موضوعية: |
Ligation, coronary vessels, rats, animal experimentation, heart surgical procedure, MYOCARDIAL-INFARCTION, RAT, 03 Good Health and Well-being, 03 Salud y bienestar |
| الوصف: |
Ligation of left anterior descending coronary artery. Surgical technique ; Background: An experimental model for ligation of the left anterior descending coronary artery (ADA) in rats has been commonly used in research into ischemic cardiopathy. However, this procedure is very difficult, with a high mortality rate. There is little information in the literature regarding its technical aspects. Our objective was to describe a surgical technique for ADA ligation in rats. Material and Method: Fifty-one Sprague-Dawley male rats weighting 230 +/- 20 gr were anaesthetized and connected to mechanical ventilation. Through a left-side thoracothomy we ligated the ADA 2 mm below the junction of the pulmonary artery and the left atrial appendage. The next day we performed transthoracic echocardiography to confirm our results. Results: The mortality rate was 7.8% (4 out of 51). The main cause of death was hemorrhage during surgery. The average time for the procedure was 45 +/- 5 min. We confirmed hypokinesia of the anterior lateral wall in 100% of the surviving rats. Discussion: This procedure was reproducible and safe, with less than 10% mortality. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
4 páginas; application/pdf |
| اللغة: |
Spanish; Castilian |
| تدمد: |
0379-3893 |
| Relation: |
https://repositorio.uc.cl/handle/11534/79494; WOS:000299365600003 |
| الاتاحة: |
https://repositorio.uc.cl/handle/11534/79494 |
| Rights: |
registro bibliográfico |
| رقم الانضمام: |
edsbas.D1644720 |
| قاعدة البيانات: |
BASE |