Academic Journal
VRD versus VCD as induction therapy before autologous stem cell transplantation in multiple myeloma: a nationwide population-based study
| العنوان: | VRD versus VCD as induction therapy before autologous stem cell transplantation in multiple myeloma: a nationwide population-based study |
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| المؤلفون: | Nørgaard, Jakob Nordberg, Moore, Kari Lenita Falck, Slørdahl, Tobias Schmidt, Vik, Anders, Tvedt, Tor Henrik Anderson, Schjesvold, Fredrik |
| بيانات النشر: | Springer Nature |
| سنة النشر: | 2024 |
| المجموعة: | University of Tromsø: Munin Open Research Archive |
| الوصف: | Induction therapy followed by autologous stem cell transplantation (ASCT) is standard of care for young and fit patients with newly diagnosed multiple myeloma (MM) [1]. Induction therapy has evolved from doublet to triplet to quadruplet regimens over the last decades. The most common triplet therapy is either Bortezomib-Cyclophosphamide-Dexamethasone (VCD), Bortezomib-Lenalidomide-Dexamethasone (VRD), or less frequently Bortezomib-Thalidomide-Dexamethasone (VTD). No large, randomized phase III study comparing the VCD and VRD regimens has been conducted and is unlikely to be done in the future. Retrospective studies and smaller prospective studies comparing VRD and VCD have produced mixed results. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2044-5385 |
| Relation: | Blood Cancer Journal; Nørgaard JN, Moore KLF, Slørdahl TS, Vik A, Tvedt THA, Schjesvold FH. VRD versus VCD as induction therapy before autologous stem cell transplantation in multiple myeloma: a nationwide population-based study. Blood Cancer Journal. 2024;14(60); FRIDAID 2261508; https://doi.org/10.1038/s41408-024-01047-1; https://hdl.handle.net/10037/33396 |
| DOI: | 10.1038/s41408-024-01047-1 |
| الاتاحة: | https://hdl.handle.net/10037/33396 https://doi.org/10.1038/s41408-024-01047-1 |
| Rights: | Attribution 4.0 International (CC BY 4.0) ; openAccess ; Copyright 2024 The Author(s) ; https://creativecommons.org/licenses/by/4.0 |
| رقم الانضمام: | edsbas.D0F87ECF |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20445385 |
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| DOI: | 10.1038/s41408-024-01047-1 |