Academic Journal
Primary pulmonary diffuse large B-cell lymphoma associated with feline leukaemia virus infection in a young cat
| العنوان: | Primary pulmonary diffuse large B-cell lymphoma associated with feline leukaemia virus infection in a young cat |
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| المؤلفون: | Ishikawa, Kento, Nagashima, Tomokazu, Machida, Yukino, Yasuda, Akiko, Yoshida, Karin, Fujita, Michio, Ochiai, Kazuhiko, Azakami, Daigo, Michishita, Masaki |
| المساهمون: | No funder |
| المصدر: | Journal of Feline Medicine and Surgery Open Reports ; volume 8, issue 1 ; ISSN 2055-1169 2055-1169 |
| بيانات النشر: | SAGE Publications |
| سنة النشر: | 2022 |
| الوصف: | Case summary A 4-year-old castrated male domestic shorthair cat with a continuous cough was brought to a private veterinary clinic for detailed examination. Radiography of the thoracic cavity revealed a severe radiopaque region in the caudal lobe of the right lung. At 108 days after the initial visit, CT showed a mass of 27 × 23 × 18 mm in the caudal lobe of the right lung. At that time, no abnormalities in other organs except for the lung were detected on CT and peripheral blood and blood biochemistry tests. The mass in the caudal lobe of the right lung was resected by lobectomy; it had a white surface and was firm. Histopathologically, the mass was non-encapsulated, showing an unclear boundary with surrounding tissues. The mass comprised large, round or polygonal neoplastic cells arranged in a diffuse pattern. Immunohistochemically, neoplastic cells were diffusely positive for CD20, feline leukaemia virus (FeLV) p27 and FeLV glycoprotein 70 but negative for CD3, CD204 and E-cadherin. Based on these findings, diffuse large B-cell lymphoma associated with FeLV infection was diagnosed. Although the cat showed no clinical signs of gastrointestinal or respiratory injury, a routine ultrasonography revealed thickening in the jejunum wall 196 days after lobectomy, and subsequent fine-needle aspiration examination confirmed high-grade lymphoma. Relevance and novel information This is the first report of primary pulmonary diffuse large B-cell lymphoma associated with FeLV infection in a young cat. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1177/20551169221074240 |
| الاتاحة: | https://doi.org/10.1177/20551169221074240 https://journals.sagepub.com/doi/pdf/10.1177/20551169221074240 https://journals.sagepub.com/doi/full-xml/10.1177/20551169221074240 |
| Rights: | https://creativecommons.org/licenses/by-nc/4.0/ |
| رقم الانضمام: | edsbas.D0F73559 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1177/20551169221074240 |
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