Academic Journal
Dynamical feature extraction at the sensory periphery guides chemotaxis
| العنوان: | Dynamical feature extraction at the sensory periphery guides chemotaxis |
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| المؤلفون: | Schulze, Aljoscha, 1980-, Gómez Marín, Alex, Rajendran, Vani G., Lott, Gus, Musy, Marco, Ahammad, Parvez, Deogade, Ajinkya, 1989-, Sharpe, James, Riedl, Julia, 1981-, Jarriault, David, Trautman, Eric T., Werner, Christopher, Venkadesan, Madhusudhan, Druckmann, Shaul, Jayaraman, Vivek, Louis, Matthieu |
| بيانات النشر: | eLife |
| سنة النشر: | 2015 |
| المجموعة: | UPF Digital Repository (Universitat Pompeu Fabra, Barcelona) |
| مصطلحات موضوعية: | Drosòfila -- Genètica, Neurones sensorials |
| الوصف: | Behavioral strategies employed for chemotaxis have been described across phyla, but the sensorimotor basis of this phenomenon has seldom been studied in naturalistic contexts. Here, we examine how signals experienced during free olfactory behaviors are processed by first-order olfactory sensory neurons (OSNs) of the Drosophila larva. We find that OSNs can act as differentiators that transiently normalize stimulus intensity—a property potentially derived from a combination of integral feedback and feed-forward regulation of olfactory transduction. In olfactory virtual reality experiments, we report that high activity levels of the OSN suppress turning, where as low activity levels facilitate turning. Using a generalized linear model, we explain how peripheral encoding of olfactory stimuli modulates the probability of switching from a run to a turn. Our work clarifies the link between computations carried out at the sensory periphery and action selection underlying navigation in odor gradients. ; This work was supported by the EU project “Marie-Curie Action: Initial Training Networks” (EC FP7-PEOPLE-2011-ITN, grant number 289941). |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | eLife. 2015;4:e06694; info:eu-repo/grantAgreement/EC/FP7/289941; http://hdl.handle.net/10230/25034; http://dx.doi.org/10.7554/eLife.06694.001 |
| DOI: | 10.7554/eLife.06694.001 |
| الاتاحة: | http://hdl.handle.net/10230/25034 https://doi.org/10.7554/eLife.06694.001 |
| Rights: | Copyright Schulze et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited. ; http://creativecommons.org/licenses/by/4.0/ ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.D0612B21 |
| قاعدة البيانات: | BASE |
| DOI: | 10.7554/eLife.06694.001 |
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