Academic Journal
Short-term and long-term risk of mortality and neurodevelopmental impairments after bacterial meningitis during infancy in children in Denmark and the Netherlands: a nationwide matched cohort study.
| العنوان: | Short-term and long-term risk of mortality and neurodevelopmental impairments after bacterial meningitis during infancy in children in Denmark and the Netherlands: a nationwide matched cohort study. |
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| المؤلفون: | Snoek, Linde, Gonçalves, Bronner P, Horváth-Puhó, Erzsébet, van Kassel, Merel N, Procter, Simon R, Søgaard, Kirstine K, Chandna, Jaya, van der Ende, Arie, van de Beek, Diederik, Brouwer, Matthijs C, Sørensen, Henrik T, Lawn, Joy E, Bijlsma, Merijn W |
| بيانات النشر: | Elsevier |
| سنة النشر: | 2022 |
| المجموعة: | London School of Hygiene & Tropical Medicine: LSHTM Research Online |
| الوصف: | BACKGROUND: Few studies have reported the long-term consequences of bacterial meningitis during infancy, and studies that have been done usually do not include a comparison cohort. We aimed to assess short-term and long-term risk of mortality, neurodevelopmental impairment (NDI), and health-care use and household income in cohorts of children with and without a history of bacterial meningitis during infancy in Denmark and the Netherlands. METHODS: In this nationwide cohort study, infants with a history of bacterial meningitis before age 1 year were identified through the Danish Medical Birth Registry and Danish National Patient Registry using International Classification of Diseases (ICD)-10 codes and through the Netherlands Reference Laboratory for Bacterial Meningitis. Infants were matched (1:10) by sex and birth month and year to a comparison cohort of the general population without a history of bacterial meningitis. We analysed mortality using Cox proportional hazards regression. In Denmark, diagnoses of NDIs were based on ICD-10 codes; in the Netherlands, special educational needs were used as a functional NDI outcome. Risk ratios (RRs) of NDIs were estimated using modified Poisson regression. We also analysed long-term health-care use in Denmark and household income in both countries. All regression analyses were adjusted for sex and year of birth, and stratified by pathogen whenever sample size allowed. FINDINGS: We included 2216 children with a history of bacterial meningitis (570 [25·7%] in Denmark between Jan 1, 1997, and Dec 31, 2018, and 1646 [74·3%] in the Netherlands between Jan 1, 1995, and Dec 31, 2018), matched to 22 127 comparison cohort members. Median age at diagnosis was 2·8 months (IQR 0·4-7·1) in Denmark and 4·3 months (0·7-7·4) in the Netherlands. Mortality risks within 3 months after disease onset were 3·9% (95% CI 2·6-5·8%) in Denmark and 5·9% (4·7-7·0) in the Netherlands, compared with 0·0% (p<0·0001) and 0·1% (p<0·0001) in the comparison cohorts. Survivors had an increased risk ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| Relation: | https://researchonline.lshtm.ac.uk/id/eprint/4667082/1/Snoek_etal_2022_Short-term-and-long-term.pdf; Snoek, Linde; Gonçalves, Bronner P; Horváth-Puhó, Erzsébet; van Kassel, Merel N; Procter, Simon R ; Søgaard, Kirstine K; Chandna, Jaya ; van der Ende, Arie; van de Beek, Diederik; Brouwer, Matthijs C; +3 more. Sørensen, Henrik T; Lawn, Joy E ; Bijlsma, Merijn W; (2022) Short-term and long-term risk of mortality and neurodevelopmental impairments after bacterial meningitis during infancy in children in Denmark and the Netherlands: a nationwide matched cohort study. The Lancet Child & Adolescent Health, 6 (9). pp. 633-642. ISSN 2352-4642 DOI: https://doi.org/10.1016/S2352-4642(22)00155-9 |
| الاتاحة: | https://researchonline.lshtm.ac.uk/id/eprint/4667082/ https://researchonline.lshtm.ac.uk/id/eprint/4667082/1/Snoek_etal_2022_Short-term-and-long-term.pdf |
| Rights: | cc_by_4 |
| رقم الانضمام: | edsbas.CFAD4999 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |