Academic Journal
Burden of Total and Cause-Specific Mortality Related to Tobacco Smoking among Adults Aged =45 Years in Asia: A Pooled Analysis of 21 Cohorts
| العنوان: | Burden of Total and Cause-Specific Mortality Related to Tobacco Smoking among Adults Aged =45 Years in Asia: A Pooled Analysis of 21 Cohorts |
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| المؤلفون: | Zheng, W., McLerran, D. F., Rolland, B. A., Fu, Z., Boffetta, P., He, J., Gupta, P. C., Ramadas, K., Tsugane, S., Irie, F., Tamakoshi, A., Gao, Y. -T., Koh, W. -P., Shu, X. -O., Ozasa, K., Nishino, Y., Tsuji, I., Tanaka, H., Chen, C. -J., Yuan, J. -M., Ahn, Y. -O., Yoo, K. -Y., Ahsan, H., Pan, W. -H., Qiao, Y. -L., Gu, D., Pednekar, M. S., Sauvaget, C., Sawada, N., Sairenchi, T., Yang, G., Wang, R., Xiang, Y. -B., Ohishi, W., Kakizaki, M., Watanabe, T., Oze, I., You, S. -L., Sugawara, Y., Butler, L. M., Kim, D. -H., Park, S. K., Parvez, F., Chuang, S. -Y., Fan, J. -H., Shen, C. -Y., Chen, Y., Grant, E. J., Lee, J. E., Sinha, R., Matsuo, K., Thornquist, M., Inoue, M., Feng, Z., Kang, D., Potter, J. D. |
| المساهمون: | Zheng, W., McLerran, D.F., Rolland, B.A., Fu, Z., Boffetta, P., He, J., Gupta, P.C., Ramadas, K., Tsugane, S., Irie, F., Tamakoshi, A., Gao, Y.-T., Koh, W.-P., Shu, X.-O., Ozasa, K., Nishino, Y., Tsuji, I., Tanaka, H., Chen, C.-J., Yuan, J.-M., Ahn, Y.-O., Yoo, K.-Y., Ahsan, H., Pan, W.-H., Qiao, Y.-L., Gu, D., Pednekar, M.S., Sauvaget, C., Sawada, N., Sairenchi, T., Yang, G., Wang, R., Xiang, Y.-B., Ohishi, W., Kakizaki, M., Watanabe, T., Oze, I., You, S.-L., Sugawara, Y., Butler, L.M., Kim, D.-H., Park, S.K., Parvez, F., Chuang, S.-Y., Fan, J.-H., Shen, C.-Y., Chen, Y., Grant, E.J., Lee, J.E., Sinha, R., Matsuo, K., Thornquist, M., Inoue, M., Feng, Z., Kang, D., Potter, J.D. |
| سنة النشر: | 2014 |
| المجموعة: | IRIS Università degli Studi di Bologna (CRIS - Current Research Information System) |
| مصطلحات موضوعية: | Tobacco smoking, cardiovascular disease, cancer, respiratory diseases |
| الوصف: | Background:Tobacco smoking is a major risk factor for many diseases. We sought to quantify the burden of tobacco-smoking-related deaths in Asia, in parts of which men's smoking prevalence is among the world's highest.Methods and Findings:We performed pooled analyses of data from 1,049,929 participants in 21 cohorts in Asia to quantify the risks of total and cause-specific mortality associated with tobacco smoking using adjusted hazard ratios and their 95% confidence intervals. We then estimated smoking-related deaths among adults aged =45 y in 2004 in Bangladesh, India, mainland China, Japan, Republic of Korea, Singapore, and Taiwan-accounting for ~71% of Asia's total population. An approximately 1.44-fold (95% CI = 1.37-1.51) and 1.48-fold (1.38-1.58) elevated risk of death from any cause was found in male and female ever-smokers, respectively. In 2004, active tobacco smoking accounted for approximately 15.8% (95% CI = 14.3%-17.2%) and 3.3% (2.6%-4.0%) of deaths, respectively, in men and women aged =45 y in the seven countries/regions combined, with a total number of estimated deaths of ~1,575,500 (95% CI = 1,398,000-1,744,700). Among men, approximately 11.4%, 30.5%, and 19.8% of deaths due to cardiovascular diseases, cancer, and respiratory diseases, respectively, were attributable to tobacco smoking. Corresponding proportions for East Asian women were 3.7%, 4.6%, and 1.7%, respectively. The strongest association with tobacco smoking was found for lung cancer: A 3- to 4-fold elevated risk, accounting for 60.5% and 16.7% of lung cancer deaths, respectively, in Asian men and East Asian women aged =45 y.Conclusions:Tobacco smoking is associated with a substantially elevated risk of mortality, accounting for approximately 2 million deaths in adults aged =45 y throughout Asia in 2004. It is likely that smoking-related deaths in Asia will continue to rise over the next few decades if no effective smoking control programs are implemented.Please see later in the article for the Editors' Summary. © 2014 Zheng et al. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | ELETTRONICO |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/wos/WOS:000335465800016; volume:11; issue:4; firstpage:0; lastpage:0; numberofpages:1; journal:PLOS MEDICINE; http://hdl.handle.net/11585/673851; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84900415399; https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1001631#ack |
| DOI: | 10.1371/journal.pmed.1001631 |
| DOI: | 10.1371/journal.pmed.1001631#ack |
| الاتاحة: | http://hdl.handle.net/11585/673851 https://doi.org/10.1371/journal.pmed.1001631 https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1001631#ack |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.CFA8A924 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1371/journal.pmed.1001631 |
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