Academic Journal
The role of white blood cell count in perianal pathologies: A retrospective analysis of hematologic malignancies
| العنوان: | The role of white blood cell count in perianal pathologies: A retrospective analysis of hematologic malignancies |
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| المؤلفون: | Orhan, Bedrettin, Özkalemkaş, Fahir, Özkocaman, Vildan, Gürbüz, Büsra, Ersal, Tuba, Pınar, İbrahim Ethem, Yalçın, Cumali, Candar, Ömer, Çubukcu, Sinem, Koca, Tuba Güllü, Ali, Rıdvan |
| المساهمون: | Bursa Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı/Hematoloji Bilim Dalı., Bursa Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı., orcid:0000-0001-9907-1498, orcid:0000-0003-4168-2821, orcid:0000-0002-5129-2977, orcid:0000-0002-5564-8862, orcid:0000-0001-7602-6926, ORHAN, BEDRETTİN, ÖZKALEMKAŞ, FAHİR, ÖZKOCAMAN, VİLDAN, GÜRBÜZ, BÜŞRA, ERSAL, TUBA, PINAR, İBRAHİM ETHEM, YALÇIN, CUMALİ, CANDAR, ÖMER, ÇUBUKÇU, SİNEM, GÜLLÜ KOCA, TÛBA, ALİ, RIDVAN, JWP-2738-2024, ACW-2157-2022, GWQ-5007-2022, KIE-5102-2024, JGM-6601-2023, GMY-8535-2022, FQG-8981-2022, JJB-0254-2023, GXD-8209-2022, AAJ-4354-2021 |
| بيانات النشر: | Mattioli 1885 |
| سنة النشر: | 2022 |
| المجموعة: | Açık Erişim@BUU (Bursa Uludağ Üniversitesi) |
| مصطلحات موضوعية: | Infections, Management, Leukemia, Perianal, Acute leukemia, White blood cell, Hematology, Infectious diseases |
| الوصف: | Background and Objective: Infections are the most common cause of anal and perianal pathologies in patients with hematological malignancies. Perianal infection diagnosis in this group of patients is difficult; thus, a careful anorectal examination is necessary with imaging modalities. In addition, the literature reveals a knowledge gap in the approach to anal pathologies in patients with neutropenia during diagnosis or chemotherapy. This study aimed to examine our institutional data on perianal complications and investigate the relationship between the white blood cell-neutrophil count, perianal lesion, and the type of treatment in patients with hematologic malignancies during the neutropenic period.Methods: Patients with a hematologic malignancy, hospitalized for cytotoxic chemotherapy, complicated by perianal pathology, documented by at least one imaging method, were included in the study.Results: A total of 42 patients were included in the study. Most of them had acute leukemia, 31 were affected by acute myeloid leukemia (AML), and 7 by Acute lymphoid leukemia (ALL). There was no statistically significant relationship between the anal abscess formation, the neutrophil count, and a previous perianal pathology. Anal abscess development was significantly more frequent in acute myeloid leukemia. An inverse relationship was found between the total white blood cell number at onset and having a surgical intervention for anal pathology.In conclusion, this article has shown that white blood cell count at the time of hospitalization can affect the surgical intervention in patients with hematological malignancy (in the majority with acute leukemia) affected by anal pathologies occurring in the neutropenic period. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2035-3006 |
| Relation: | Makale - Uluslararası Hakemli Dergi; Mediterranean Journal of Hematology and Infectious Diseases; https://doi.org/10.4084/MJHID.2022.051; https://www.mjhid.org/index.php/mjhid/article/view/4989; https://hdl.handle.net/11452/44408; 000818865900006; 14 |
| DOI: | 10.4084/MJHID.2022.051 |
| الاتاحة: | https://hdl.handle.net/11452/44408 https://doi.org/10.4084/MJHID.2022.051 https://www.mjhid.org/index.php/mjhid/article/view/4989 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.CF07C00D |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20353006 |
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| DOI: | 10.4084/MJHID.2022.051 |