Academic Journal
Can systemic inflammatory markers predict sperm retrieval with the micro-TESE procedure in patients with non-obstructive azoospermia? A tertiary IVF center experience
| العنوان: | Can systemic inflammatory markers predict sperm retrieval with the micro-TESE procedure in patients with non-obstructive azoospermia? A tertiary IVF center experience |
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| المؤلفون: | Çöğendez, Ebru, Devranoğlu, Belgin, Aras, Alı, Köse, Gökşen Derya Reis, Tozkır, Elif, Kumru, Pınar, Özkaya, Enis |
| سنة النشر: | 2022 |
| الوصف: | Objective: We aim to investigate the relationship between the pro-inflammatory mark- ers and sperm retrieval (SR) in microdissection testicular sperm extraction (micro- TESE) procedure in patients with non-obstructive azoospermia (NOA). Material and Methods: This retrospective study was conducted with 318 patients who applied to our in vitro fertilization Unit between April 2017 and December 2020 and underwent micro-TESE for NOA. Patients with (Group 1) and without (Group 2) sperm retrieved were compared in terms of age, infertility duration, body mass index (BMI), hormone profile, neutrophil-to-lymphocyte ratio (NLR), monocyte-to-eosinophil ratio (MER), platelet-to-lymphocyte ratio (PLR), and a new marker of eosinophil-to- lymphocyte ratio (ELR). Results: SR from the micro-TESE procedure was achieved in 183 (57.5%) of 318 patients. Testicular tissue biopsies were performed simultaneously in all cases. There was no statistically significant difference between the groups concerning BMI. When the groups were compared regarding the pro-inflammatory markers, while the NLR, MER, and PLR were found to be statistically higher in Group 2 cases; ELR was similar among groups. Conclusion: The MER, NLR, and PLR were determined to be associated with neg- ative micro-TESE results. Particularly PLR seems to have a poor prognostic value in these patients. A prognostic value of the ELR which was a new biomarker was not determined in SR from the TESE procedure. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2757-8062 |
| Relation: | Zeynep Kamil medical journal (Online); Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı; https://doi.org/10.14744/zkmj.2022.46704; https://search.trdizin.gov.tr/yayin/detay/1171065; https://hdl.handle.net/11468/28448; 53; 176; 182; 1171065 |
| DOI: | 10.14744/zkmj.2022.46704 |
| الاتاحة: | https://hdl.handle.net/11468/28448 https://doi.org/10.14744/zkmj.2022.46704 https://search.trdizin.gov.tr/yayin/detay/1171065 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.CE873A1C |
| قاعدة البيانات: | BASE |
| تدمد: | 27578062 |
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| DOI: | 10.14744/zkmj.2022.46704 |