Academic Journal
Daycare use of disinfectants and cleaning products and wheeze among children: Cross-sectional analyses in the French CRESPI cohort
| العنوان: | Daycare use of disinfectants and cleaning products and wheeze among children: Cross-sectional analyses in the French CRESPI cohort |
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| المؤلفون: | Bright, Franziska, Pacheco da Silva, Emilie, Amat, Flore, Bonnet, Pierre, Eworo Nchama, Anastasie, Sévin, Etienne, Siroux, Valérie, Mandin, Corinne, Le Moual, Nicole, Dumas, Orianne |
| المساهمون: | Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Hôpital Robert Debré, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre Scientifique et Technique du Bâtiment (CSTB), EpiConcept Paris, Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (IAB), Centre Hospitalier Universitaire CHU Grenoble (CHUGA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Funding for the CRESPI cohort was provided by Anses (Anses-PNR-EST-2017-1-101), Ademe (1762C0021), Fondation de France (00081167), ARS Ile de France (2018-2019), and ANR (ANR-18-CE36-0002). The CRESPI Scientific committee includes Nicole Le Moual, Orianne Dumas, Flore Amat (Inserm U1018, CESP, Villejuif), Val\u00E9rie Siroux (Inserm U1209, Grenoble), Barbara Le Bot (EHESP, Inserm IRSET, Rennes), C\u00E9cile Chevrier (Inserm IRSET, EHESP, Rennes), and Corinne Mandin (IRSN, Fontenay aux Roses). The authors would like to thank all Inserm and CSTB staff who participated in setting up the CRESPI study, especially the air quality technicians, fieldworkers, and people involved in quality control and data management. The authors extend special thanks to the following Inserm (Inserm U1018, CESP, Villejuif) staff: Anastasie Eworo Nchama, Clemence Guilhen, Samira Medjahed, and St\u00E9phanie Raoult des Essarts for their involvement with the protocol and set-up of the survey, logistical organization and visits to daycares, Abderrezack Tafer, Jean-Charles Lodin, Emilie Pacheco Da Silva, Lina Meziani, Samy Dehissi, Rozenn Delabarre, and Sarah Emamdjomeh for their implication in the study and/or visits to daycares during their internships, Samy Dehissi and Rozenn Delabarre for recording the complete compounds list of cleaning products scanned in daycares, Sarah Idrisse Abdou, Giovanni Paparella, and Hadja Ndiaye for data entry, Lobna Tijani, Franziska Bright and Chlo\u00E9 Landais for their involvement in the study, data quality checks, data management and statistical analysis during their internships, and Annabelle B\u00E9dard for her implication during her post-doc (Inserm CESP, Villejuif). The authors thank Pierre Bonnet, Doriane Rousselle, Linda Bessaa, Sharmila Thangarajah, Vincent Amaru, Isabelle Lacaze, and Sutharsini Sivanantham from CSTB (Champs-sur-Marne), M\u00E9lanie Nicolas (CSTB, Grenoble), Etienne S\u00E9vin and St\u00E9phanie Ployard from Epiconcept (Paris), and Ga\u00EBlle Saramito, Ga\u00EBlle Raffy and Mayoro Men\u00E9 from EHESP (Rennes), for their involvement in the study. A warm thank you also to Isabelle Pin (Inserm U1209, CHU Grenoble, 2019\u20132022) and Flore Amat (Inserm U1018, CHU Robert-Debr\u00E9, Paris, 2022) for serving as clinician experts for the CRESPI study. Lastly, we are grateful to all the daycare workers and parents who participated in the CRESPI cohort, without whom the study would not have been possible., Funding for the CRESPI cohort was provided by Anses ( Anses-PNR-EST-2017-1-101 ), Ademe ( 1762C0021 ), Fondation de France ( 00081167 ), ARS Ile de France (2018-2019), and ANR ( ANR-18-CE36-0002 )., ANR-18-CE36-0002,CRESMINA,Environnement en crèche, microbiote nasal et santé respiratoire de jeunes enfants(2018) |
| المصدر: | ISSN: 0048-9697. |
| بيانات النشر: | CCSD Elsevier |
| سنة النشر: | 2024 |
| مصطلحات موضوعية: | Child wheeze, Cleaning products, Daycare, Indoor environmental exposures, Respiratory health, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, [SDV.EE.SANT]Life Sciences [q-bio]/Ecology, environment/Health, [SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatrics, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract |
| الوصف: | International audience ; Background: Evidence is mounting that domestic use of disinfectants and cleaning products (DCP), particularly in spray form, is associated with wheezing in children. Beyond the home environment, many children are also exposed to DCP in daycare. The links between daycare exposures to DCP and child respiratory health have never before been studied.Objectives: Evaluate the associations between daycare DCP use and wheeze among children.Methods: This cross-sectional study draws upon the data at inclusion for 536 children (mean age: 22.3 months; 47.4 % female) of the French CRESPI cohort (108 daycares in the Paris region, 2019–2022). Exposure to DCP was evaluated using a barcode-scanning smartphone application with an embedded questionnaire. An exposure score was calculated as the sum of frequencies of use of DCP for each daycare. Child wheezing outcomes (ever wheeze since birth, recurrent wheeze (≥3 times since birth), and wheeze ever treated with inhaled corticosteroids (ICS)) were evaluated by parental questionnaire. Associations between daycare DCP exposure and wheezing outcomes were analyzed with Generalized Estimating Equations to account for a possible center effect, and adjusted for child age, parental smoking status, parental educational attainment, and daycare size.Results: The prevalence of ever wheeze was 32.1 %, that of recurrent wheeze 13.3 %, and that of wheeze ever treated with ICS 14.5 %. Above-median exposure scores (vs. ≤ median exposure scores) were associated with higher odds of wheeze ever treated with ICS (Odds Ratio = 1.72, 95 % Confidence Interval: 1.07–2.75) and ever wheeze (1.40, 0.98–2.00), but not with recurrent wheeze (1.35, 0.79–2.31). Relationships between specific DCP application modes and wheezing outcomes did not suggest a predominant role of specific modes.Discussion: Given the observed association between daycare DCP use and wheeze in children, measures which limit child exposure to DCP in care settings should be considered. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1016/j.scitotenv.2024.178016 |
| الاتاحة: | https://hal.science/hal-04867652 https://hal.science/hal-04867652v1/document https://hal.science/hal-04867652v1/file/1-s2.0-S0048969724081737-main.pdf https://doi.org/10.1016/j.scitotenv.2024.178016 |
| Rights: | http://creativecommons.org/licenses/by/ ; info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.CE338488 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.scitotenv.2024.178016 |
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