Academic Journal
COX‐2 in the neurodegenerative process of Parkinson's disease
| العنوان: | COX‐2 in the neurodegenerative process of Parkinson's disease |
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| المؤلفون: | Teismann, Peter |
| المصدر: | BioFactors ; volume 38, issue 6, page 395-397 ; ISSN 0951-6433 1872-8081 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2012 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | The enzyme cyclooxygenase‐2 (COX‐2), responsible for the first committed step in the synthesis of several important mediators which are involved in both initiation and resolution of inflammation, and the subsequent generation of prostaglandins (PGs) upon activation has been shown to participate in the neurodegenerative processes of a variety of diseases. This review looks particular at the role of COX‐2 in the pathogenesis of Parkinson's disease, involving the generation of PGs and the role of the two different parts of the cyclooxygenase—cyclooxygenase and peroxidase activity. © 2012 International Union of Biochemistry and Molecular Biology, Inc. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1002/biof.1035 |
| الاتاحة: | http://dx.doi.org/10.1002/biof.1035 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbiof.1035 https://onlinelibrary.wiley.com/doi/pdf/10.1002/biof.1035 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/biof.1035 https://iubmb.onlinelibrary.wiley.com/doi/pdf/10.1002/biof.1035 |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.CDF0255E |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/biof.1035 |
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