Academic Journal
The Prognostic Role of Polysomnography Parameters in Heart Failure Patients with Previous Decompensation
| العنوان: | The Prognostic Role of Polysomnography Parameters in Heart Failure Patients with Previous Decompensation |
|---|---|
| المؤلفون: | Elena Medvedeva, Lyudmila Korostovtseva, Mihail Bochkarev, Anastasiya Shumeiko, Aelita Berezina, Maria Simonenko, Yulia Sazonova, Andrey Kozlenok, Yurii Sviryaev |
| المصدر: | Journal of Clinical Medicine, Vol 11, Iss 3656, p 3656 (2022) |
| بيانات النشر: | MDPI AG |
| سنة النشر: | 2022 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | heart failure, sleep apnea, prognosis, polysomnography, wake after sleep onset, Medicine |
| الوصف: | Background: Sleep-disordered breathing (SDB) is a widespread comorbidity in patients with chronic heart failure (HF) and may have a deleterious effect on the pathogenesis of HF. We aimed to evaluate the prognostic role of polysomnography parameters in HF patients with previous decompensation. Methods: 123 patients were included in the prospective cohort study. In addition to the standard examination, all patients underwent polysomnography (PSG). Results: The Kaplan–Meier analysis showed the incidence of the combined endpoint differs between LVEF categories ≤25.5% vs. >25.5% (χ 2 = 9.6, log rank p = 0.002), NTpro-BNP > 680 vs. ≤680 pg/mL (χ 2 = 12.7, log rank p = 0.001), VO 2 peak categories <16 vs. ≥16 mL/min/kg (χ 2 = 14.2, log rank p = 0.001), VE/VCO 2 slope ≥38.5 vs. <38.5 (χ 2 = 14.5, log rank p = 0.001), wake after sleep onset >40 min vs. ≤40 min (χ 2 = 9.7, log rank p = 0.03), and sleep stage 2 (S 2 ) <44% vs. ≥44% (χ 2 = 12.4, log rank p = 0.001). Conclusion: Among the PSG parameters, WASO > 40 min and S 2 < 44% were associated with a combined endpoint in patients with previous decompensation of HF. Moreover, higher NT-proBNP and VE/VCO 2 slope, lower LVEF, and VO 2peak were also independent factors of a poor prognosis. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2077-0383 |
| Relation: | https://www.mdpi.com/2077-0383/11/13/3656; https://doaj.org/toc/2077-0383; https://doaj.org/article/29f2e6c58f7146379d05ed6db9c34418 |
| DOI: | 10.3390/jcm11133656 |
| الاتاحة: | https://doi.org/10.3390/jcm11133656 https://doaj.org/article/29f2e6c58f7146379d05ed6db9c34418 |
| رقم الانضمام: | edsbas.CDC32F6E |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20770383 |
|---|---|
| DOI: | 10.3390/jcm11133656 |