Academic Journal
Serial echocardiographic evaluation of COVID-19 patients without prior history of structural heart disease: a 1-year follow-up CRACoV-HHS study
| العنوان: | Serial echocardiographic evaluation of COVID-19 patients without prior history of structural heart disease: a 1-year follow-up CRACoV-HHS study |
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| المؤلفون: | Olszanecka, Agnieszka, Wojciechowska, Wiktoria, Bednarek, Agnieszka, Kusak, Piotr, Wizner, Barbara, Terlecki, Michał, Stolarz-Skrzypek, Katarzyna, Klocek, Marek, Drożdż, Tomasz, Sładek, Krzysztof, Bociąga-Jasik, Monika, Garlicki, Aleksander, Rewiuk, Krzysztof, Matyja, Andrzej, Małecki, Maciej, Sydor, Wojciech, Krzanowski, Marcin, Grodzicki, Tomasz, Rajzer, Marek |
| المصدر: | Frontiers in Cardiovascular Medicine ; volume 10 ; ISSN 2297-055X |
| بيانات النشر: | Frontiers Media SA |
| سنة النشر: | 2023 |
| المجموعة: | Frontiers (Publisher - via CrossRef) |
| الوصف: | Background It is a well-known fact that COVID-19 affects the cardiovascular system by exacerbating heart failure in patients with preexisting conditions. However, there is a poor insight into the cardiovascular involvement and sequelae in patients without preexisting conditions. The aim of the study is to analyse the influence of COVID-19 on cardiac performance in patients without prior history of structural heart disease. The study is part of the CRACoV project, which includes a prospective design and a 12-month follow-up period. Material and methods The study included 229 patients hospitalised with a diagnosis of COVID-19 (median age of 59 years, 81 were women). A standard clinical assessment and laboratory tests were performed in all participants. An extended echocardiographic image acquisition was performed at baseline and at a 3-, 6-, and 12-month follow-up. All analyses were performed off-line. A series of echocardiographic parameters was compared using repeated measures or Friedman analysis of variance. Results In all subjects, the left ventricular (LV) ejection fraction at baseline was preserved [63.0%; Q1:Q3 (60.0–66.0)]. Elevated levels of high-sensitivity cardiac troponin T were detected in 21.3% of the patients, and elevated NT-proBNP levels were detected in 55.8%. At the 1-year follow-up, no significant changes were observed in the LV diameter and volume (LV 48.0 ± 5.2 vs. 47.8 ± 4.8 mm, p = 0.08), while a significant improvement of the parameters in the biventricular strain was observed (LV −19.1 ± 3.3% vs. −19.7 ± 2.5%, p = 0.01, and right ventricular −19.9 ± 4.5% vs. −23.2 ± 4.9%, p = 0.002). In addition, a decrease in the LV wall thickness was also observed (interventricular septum 10.4 ± 1.6 vs. 9.7 ± 2.0 mm, p < 0.001; LV posterior wall 9.8 ± 1.4 vs. 9.1 ± 1.5 mm, p < 0.001). Conclusions In an acute phase of COVID-19, the elevation of cardiac biomarkers in patients with normal left ventricular ejection fraction is a frequent occurrence; however, it does not translate into ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| DOI: | 10.3389/fcvm.2023.1230669 |
| DOI: | 10.3389/fcvm.2023.1230669/full |
| الاتاحة: | http://dx.doi.org/10.3389/fcvm.2023.1230669 https://www.frontiersin.org/articles/10.3389/fcvm.2023.1230669/full |
| Rights: | https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: | edsbas.CD3F64C5 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3389/fcvm.2023.1230669 |
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