التفاصيل البيبلوغرافية
| العنوان: |
Oral squamous cell carcinoma involving the maxillae: Factors affecting local recurrence and the value of salvage treatment for overall survival |
| المؤلفون: |
Slieker, Fons J B, de Bree, Remco, Van Cann, Ellen M |
| المساهمون: |
MS Hoofd-Hals Chirurgische Oncologie, Cancer |
| سنة النشر: |
2020 |
| مصطلحات موضوعية: |
5-year local control, malignancy, maxillary cancer, maxillectomy, salvage treatment, squamous cell carcinoma, Otorhinolaryngology, Journal Article |
| الوصف: |
OBJECTIVE: To determine factors associated with local recurrence (LR) of oral squamous cell carcinoma involving the maxillae (MSCC) and overall survival (OS) after salvage treatment. SUBJECTS AND METHODS: Retrospective study of MSCC operated between 2000 and 2015. Kaplan-Meier survival and Cox regression were used for analysis of MSCC-associated clinical and histopathological factors. RESULTS: Ninety-five patients were included. LR occurred in 24% of patients. Vascular invasion significantly increased the risk of LR (hazard ratio 4.595, P = .003). Local salvage surgery, in the area of the original tumor, significantly prolonged OS, compared to palliative treatment (P = .001) and extensive salvage surgery (P = .013). Extensive salvage surgery, requiring resection of adjacent facial structures, did not prolong OS compared to palliative treatment (P = .186). CONCLUSIONS: MSCC with vascular invasion has higher risk of LR. Salvage surgery may prolong OS in small recurrences but might have dubious value for larger recurrences infiltrating adjacent facial structures. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| تدمد: |
1043-3074 |
| Relation: |
https://dspace.library.uu.nl/handle/1874/439480 |
| الاتاحة: |
https://dspace.library.uu.nl/handle/1874/439480 |
| Rights: |
info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: |
edsbas.CC317BEC |
| قاعدة البيانات: |
BASE |