التفاصيل البيبلوغرافية
| العنوان: |
Investigation of Anthelmintic Potential of Two Leafy Vegetables from the Amaranthaceae Family |
| المؤلفون: |
Tripathi, Manju, Adsul, Vaishali B., E. Khatiwora, Wadekar, M. P., Gaikwad, S. A. |
| المصدر: |
Journal of Natural Remedies; Volume 24, Issue 1, January 2024; 127-134 ; 2320-3358 ; 0972-5547 |
| بيانات النشر: |
Informatics Publishing Limited and Natural Remedies Pvt. Ltd. |
| سنة النشر: |
2024 |
| المجموعة: |
Informatics Journals (Informatics Publishing Ltd.) |
| مصطلحات موضوعية: |
Albendazole, Amaranthus tricolor Linn., Amaranthus viridis Linn., Anthelmintic Activity, Earthworm, Eisenia fetida |
| الوصف: |
Objective: The present study investigates the anthelmintic potential of Amaranthus viridis Linn. and Amaranthus tricolor Linn. (Amaranthaceae) leafy vegetables from the Pune district, traditionally used as vermicides. Materials and Methods:The ethyl acetate, acetone and ethanol leaf extracts of both plants were subjected to preliminary investigations for thephytochemical elements. The anthelmintic activity of these extracts was tested against fully-grown Eisenia fetida earthworms.Ethyl acetate extract of A. viridis L. and acetone extract of Amaranthus tricolor L. showed the presence of all phytochemicals.Doses of 10–30 mg/ml were used in bioassay. Time of paralysis and death of earthworms was observed. Results: All extractsexhibited considerable dose-dependent activity against the reference drug, showing maximum activity at 30 mg/mL in bothplants. The most promising activity was exhibited by the ethyl acetate extract of the A. viridis L. (P (min.) = 4, D (min.) =5), followed by the acetone extract of the A. tricolor L. (P (min.) = 6, D (min.) = 13). Albendazole (20 mg/ml) and normalsaline were applied as a standard drug and control, respectively. High concentrations of alkaloids, tannins, and phenolicphytochemicals might be responsible for the exceptional activity. Conclusion: The present work scientifically validates thetraditional use and concludes that ethyl acetate and acetone extracts may be further processed to isolate the compoundsresponsible for said activity. One-way ANOVA with a significance level of 5% was used to validate the data (n = 3, p < 0.05). |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| Relation: |
https://www.informaticsjournals.com/index.php/jnr/article/view/34714/23111; https://www.informaticsjournals.com/index.php/jnr/article/view/34714 |
| الاتاحة: |
https://www.informaticsjournals.com/index.php/jnr/article/view/34714 |
| Rights: |
Copyright (c) 2024 Manju Tripathi, Vaishali B. Adsul, E. Khatiwora, M. P. Wadekar, S. A. Gaikwad (Author) ; http://creativecommons.org/licenses/by/4.0 |
| رقم الانضمام: |
edsbas.C9ACB1B5 |
| قاعدة البيانات: |
BASE |