التفاصيل البيبلوغرافية
| العنوان: |
Effects of dietary polyphenol intake on metabolic syndrome, body composition and obesity-related inflammation |
| المؤلفون: |
Castro Barquero, Sara |
| المساهمون: |
Estruch Riba, Ramon, Tresserra i Rimbau, Anna, Universitat de Barcelona. Facultat de Medicina i Ciències de la Salut |
| المصدر: |
TDX (Tesis Doctorals en Xarxa) |
| بيانات النشر: |
Universitat de Barcelona |
| سنة النشر: |
2023 |
| المجموعة: |
Universitat de Barcelona: Tesis Doctorals en Xarxa (TDX) / Theses and Dissertations Online |
| مصطلحات موضوعية: |
Polifenols, Polifenoles, Polyphenols, Síndrome metabòlica, Síndrome metabólico, Metabolic syndrome, Cuina mediterrània, Cocina mediterránea, Mediterranean cooking, Obesitat, Obesidad, Obesity, Malalties cardiovasculars, Enfermedades cardiovasculares, Cardiovascular diseases, Ciències de la Salut, 616.1 |
| الوصف: |
Programa de Doctorat en Medicina i Recerca Translacional ; [eng] INTRODUCTION: Metabolic syndrome (MetS) is a clustering of different cardiovascular and cardiometabolic risk factors. In developed countries, MetS prevalence has risen to 20- 25% in the adult population, and its incidence is increasing. Public health strategies for MetS treatment and prevention are mainly focused on lifestyle modification, including dietary and physical activity promotion. Aligned with MetS, obesity is a multifactorial complex disease defined by excess of adipose mass, which occurs through adipocyte hypertrophy and hyperplasia. However, while waist circumference is a better predictor for CVD than BMI or body weight, it is an index of total adiposity, and it cannot differentiate visceral from subcutaneous adiposity. The adipose tissue is an endocrine organ that secretes a wide variety of inflammatory adipocytokines, such as TNF-alpha, IL-6, resistin, leptin, and adiponectin. Visceral adiposity is associated with a higher production of these inflammatory adipocytokines, leading to systemic inflammation, insulin resistance, and several obesity-related metabolic disorders. Phenolic compounds, also known as polyphenols, are characterized by the presence of one or more aromatic rings and phenol structural units in its molecules. The main food sources of polyphenols in Mediterranean countries are coffee, fruits, red wine, and vegetable oils, especially olive oil, whereas in non-Mediterranean countries, coffee, tea, fruits, and wine were the main food sources. Moreover, a continuous and prolonged polyphenol intake is related to BP and adiposity lowering effects, improvements in lipid profile, and anti-inflammatory effects, which all act as CVD protectors. OBJECTIVE: The general objective of this thesis project is to evaluate the effect of a high dietary polyphenol intake included in an intensive weight-loss-oriented lifestyle intervention program on adiposity parameters and other cardiovascular risk factors in patients with MetS, as well ... |
| نوع الوثيقة: |
doctoral or postdoctoral thesis |
| وصف الملف: |
275 p.; application/pdf |
| اللغة: |
English |
| Relation: |
http://hdl.handle.net/10803/687375 |
| الاتاحة: |
http://hdl.handle.net/10803/687375 |
| Rights: |
ADVERTIMENT. Tots els drets reservats. L'accés als continguts d'aquesta tesi doctoral i la seva utilització ha de respectar els drets de la persona autora. Pot ser utilitzada per a consulta o estudi personal, així com en activitats o materials d'investigació i docència en els termes establerts a l'art. 32 del Text Refós de la Llei de Propietat Intel·lectual (RDL 1/1996). Per altres utilitzacions es requereix l'autorització prèvia i expressa de la persona autora. En qualsevol cas, en la utilització dels seus continguts caldrà indicar de forma clara el nom i cognoms de la persona autora i el títol de la tesi doctoral. No s'autoritza la seva reproducció o altres formes d'explotació efectuades amb finalitats de lucre ni la seva comunicació pública des d'un lloc aliè al servei TDX. Tampoc s'autoritza la presentació del seu contingut en una finestra o marc aliè a TDX (framing). Aquesta reserva de drets afecta tant als continguts de la tesi com als seus resums i índexs. ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.C92F113F |
| قاعدة البيانات: |
BASE |