Academic Journal

Sensitivity of Strains of Meticillin Resistant Staphylococcus aureus (MRSA), Isolated from Bacterial Infections in the District of Abidjan

التفاصيل البيبلوغرافية
العنوان: Sensitivity of Strains of Meticillin Resistant Staphylococcus aureus (MRSA), Isolated from Bacterial Infections in the District of Abidjan
المؤلفون: Dibolou Sandrine , Louah, Eric Joël , Tahou, Fernique , Konan, Kouadio Nathalie , Guessennd, Assanvo Simon-Pierre , N’guetta
المصدر: Journal of Advances in Biology & Biotechnology; 2022 - Volume 25 [Issue 10]; 41-47 ; 2394-1081
بيانات النشر: SCIENCEDOMAIN international
سنة النشر: 2022
مصطلحات موضوعية: Staphylococcus aureus, epidemiology, antibiotics, resistance to methicillin, Abidjan
الوصف: Staphylococcus aureus is one of the most prevalent human pathogens causing a wide range of bacterial infections. Since the introduction of methicillin as a treatment option, the emergence and subsequent spread of methicillin-resistant Staphylococcus aureus (MRSA) strains has become a global concern. The objective of this study is to determine the prevalence of MRSA isolated from bacterial infections in Abidjan as well as their resistance profile to certain antibiotics. One hundred and twenty-four (124) strains of Staphylococcus aureus from the University Hospital of Cocody and various clinics isolated from various biological products were included in our study. The antibiogram on Mueller-Hinton agar was repeated by testing cefoxitin for the revelation of MRSA. Several other families of antibiotics have also been tested with the aim of observing resistance associated with MRSA. Among the one hundred and twenty-four strains of Staphylococcus aureus analyzed, 75 present, after phenotypic interpretation, a profile of resistance to methicillin (MRSA strains), i.e. 60.48%. These MRSA were isolated from blood culture (26.67%), purulent secretions (44%), urine (14.67%), sperm culture (1.33%), wound (4%), pleural fluid (4%), stool (1.33%) and tip of urinary catheter (4%); and came from neonatology, surgery, pneumology, pediatrics, outpatient, medicine, emergency, rheumatology, ENT, neurology, traumatology and gastroenterology departments. A variable proportion of MRSA strains express resistance to other families of antibiotics including aminoglycosides (23.32%), fluoroquinolones (85.33%), erythromycin (27.64%), clindamycin (24.19%) and tetracycline (20.73%). The increasing prevalence of multidrug-resistant Staphylococcus aureus, limiting the therapeutic options available against this pathogen, has become an issue of concern worldwide. Thus, the establishment of a relevant resistance monitoring policy to better control the circulation of multi-resistant strains is necessary.
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: English
Relation: http://journaljabb.com/index.php/JABB/article/view/603/1209; http://journaljabb.com/index.php/JABB/article/view/603/1210; http://journaljabb.com/index.php/JABB/article/view/603
DOI: 10.9734/jabb/2022/v25i10603
الاتاحة: http://journaljabb.com/index.php/JABB/article/view/603
https://doi.org/10.9734/jabb/2022/v25i10603
Rights: Copyright (c) 2022 Sandrine et al.; This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
رقم الانضمام: edsbas.C8FB5D26
قاعدة البيانات: BASE
الوصف
DOI:10.9734/jabb/2022/v25i10603