Academic Journal
General methodology for the chemoselective N-alkylation of (2,2,6,6)-tetramethylpiperidin-4-ol: Contribution of microwave irradiation
| العنوان: | General methodology for the chemoselective N-alkylation of (2,2,6,6)-tetramethylpiperidin-4-ol: Contribution of microwave irradiation |
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| المؤلفون: | Membrat, Romain, Vasseur, Alexandre, Giordano, Laurent, Martinez, Alexandre, Nuel, Didier |
| المساهمون: | Institut des Sciences Moléculaires de Marseille (ISM2), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Lorrain de Chimie Moléculaire (L2CM), Institut de Chimie - CNRS Chimie (INC-CNRS)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS) |
| المصدر: | ISSN: 0040-4039. |
| بيانات النشر: | HAL CCSD Elsevier |
| سنة النشر: | 2019 |
| المجموعة: | Université de Lorraine: HAL |
| مصطلحات موضوعية: | [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.INOR]Chemical Sciences/Inorganic chemistry |
| الوصف: | International audience ; A convenient method to access a broad variety of N-alkyl-(2,2,6,6)-tetramethylpiperidin-4-ol compounds is reported. The thermal treatment of a mixture of (2,2,6,6)-tetramethylpiperidin-4-ol and allyl or benzyl bromide derivatives gave the corresponding N–alkylated compounds in good yields while leaving the hydroxyl functional group intact. Whereas 40 h were needed to reach complete conversion, microwave irradiation allowed the reaction time to be reduced (20 min) and improved the yields in most cases. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | hal-01969189; https://hal.univ-lorraine.fr/hal-01969189; https://hal.univ-lorraine.fr/hal-01969189/document; https://hal.univ-lorraine.fr/hal-01969189/file/RM_2019.pdf |
| DOI: | 10.1016/j.tetlet.2018.12.020 |
| الاتاحة: | https://hal.univ-lorraine.fr/hal-01969189 https://hal.univ-lorraine.fr/hal-01969189/document https://hal.univ-lorraine.fr/hal-01969189/file/RM_2019.pdf https://doi.org/10.1016/j.tetlet.2018.12.020 |
| Rights: | http://creativecommons.org/licenses/by-nc-nd/ ; info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.C871DC8D |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.tetlet.2018.12.020 |
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