Academic Journal

Autoimmune Diseases of Digestive Organs—A Multidisciplinary Challenge: A Focus on Hepatopancreatobiliary Manifestation

التفاصيل البيبلوغرافية
العنوان: Autoimmune Diseases of Digestive Organs—A Multidisciplinary Challenge: A Focus on Hepatopancreatobiliary Manifestation
المؤلفون: Lumir Kunovsky, Petr Dite, Petr Jabandziev, Zdenek Kala, Jitka Vaculova, Tomas Andrasina, Matej Hrunka, Martina Bojkova, Jan Trna
المصدر: Journal of Clinical Medicine; Volume 10; Issue 24; Pages: 5796
بيانات النشر: Multidisciplinary Digital Publishing Institute
سنة النشر: 2021
المجموعة: MDPI Open Access Publishing
مصطلحات موضوعية: human leukocyte antigen, celiac disease, inflammatory bowel disease, autoimmune hepatitis, primary sclerosing cholangitis, primary biliary cholangitis, autoimmune pancreatitis, IgG4-related sclerosing cholangitis, IgG4-related hepatopathy
الوصف: It is well known that some pathological conditions, especially of autoimmune etiology, are associated with the HLA (human leukocyte antigen) phenotype. Among these diseases, we include celiac disease, inflammatory bowel disease, autoimmune enteropathy, autoimmune hepatitis, primary sclerosing cholangitis and primary biliary cholangitis. Immunoglobulin G4-related diseases (IgG4-related diseases) constitute a second group of autoimmune gastrointestinal, hepatobiliary and pancreatic illnesses. IgG4-related diseases are systemic and rare autoimmune illnesses. They often are connected with chronic inflammation and fibrotic reaction that can occur in any organ of the body. The most typical feature of these diseases is a mononuclear infiltrate with IgG4-positive plasma cells and self-sustaining inflammatory response. In this review, we focus especially upon the hepatopancreatobiliary system, autoimmune pancreatitis and IgG4-related sclerosing cholangitis. The cooperation of the gastroenterologist, radiologist, surgeon and histopathologist is crucial for establishing correct diagnoses and appropriate treatment, especially in IgG4 hepatopancreatobiliary diseases.
نوع الوثيقة: text
وصف الملف: application/pdf
اللغة: English
Relation: Gastroenterology & Hepatopancreatobiliary Medicine; https://dx.doi.org/10.3390/jcm10245796
DOI: 10.3390/jcm10245796
الاتاحة: https://doi.org/10.3390/jcm10245796
Rights: https://creativecommons.org/licenses/by/4.0/
رقم الانضمام: edsbas.C78F41A9
قاعدة البيانات: BASE