Academic Journal

Association between anhedonia and suicidal events in patients with mood disorders: A 3-year prospective study.

التفاصيل البيبلوغرافية
العنوان: Association between anhedonia and suicidal events in patients with mood disorders: A 3-year prospective study.
المؤلفون: Ducasse, D., Dubois, J., Jaussent, I., Azorin, J. M., Etain, B., Gard, S., Henry, C., Bougerol, T., Kahn, J. P., Aubin, V., Bellivier, F., Belzeaux, R., Dubertret, C., Dubreucq, J., Llorca, P. M., Loftus, J., Passerieux, C., Polosan, M., Samalin, L., Leboyer, M., Yrondi, A., Bennabi, D., Haffen, E., Maruani, J., Allauze, E., Camus, V., D'amato, T., Doumy, O., Holtzmann, J., Lançon, C., Moliere, F., Moirand, R., Richieri, R. M., Horn, Mathilde, Schmitt, L., Stephan, F., Genty, J. B., Vaiva, Guillaume, Walter, M., El-Hage, W., Aouizerate, B., Olié, E., Courtet, P.
المساهمون: Université de Lille, Inserm, CHU Lille, Centre Hospitalier Régional Universitaire Montpellier CHRU Montpellier, Université Paul-Valéry - Montpellier 3 UPVM, University Hospital of Montpellier, Département Universitaire de Psychiatrie - Hôpital Sainte Marguerite - APHM Hôpitaux Sud, Fondation FondaMental Créteil, Hôpital Henri Mondor, Centre hospitalier Charles Perrens Bordeaux, Université Paris-Est UPE, Pôle Psychiatrie et Neurologie Grenoble, Centre Hospitalier Princesse Grace, Hôpitaux Universitaires Saint-Louis, Lariboisière, Fernand-Widal, Centre de recherche en neurobiologie - neurophysiologie de Marseille CRN2M, Hôpital Louis Mourier - AP-HP Colombes, Centre Hospitalier Universitaire CHU Grenoble CHUGA, Service Psychiatrie Adulte CHU Clermont-Ferrand, Centre Hospitalier de Versailles André Mignot CHV, GIN Grenoble Institut des Neurosciences GIN, CHU Clermont-Ferrand, Centre Hospitalier Universitaire de Toulouse CHU Toulouse, Université Bourgogne Franche-Comté COMUE UBFC, Hôpital Lariboisière-Fernand-Widal APHP, Centre Hospitalier le Vinatier Bron, Hôpital de la Conception CHU - APHM LA CONCEPTION, Lille Neurosciences & Cognition (LilNCog) - U 1172, Centre Hospitalier Régional Universitaire de Brest CHRU Brest, Centre Hospitalier Régional Universitaire de Tours CHRU Tours
بيانات النشر: Wiley
سنة النشر: 2024
المجموعة: LillOA (Lille Open Archive - Université de Lille)
مصطلحات موضوعية: suicide attempt, suicidal ideation, prospective study, mood disorder, anhedonia
الوصف: Background As almost all mental disorders are associated with increased suicidal-related behavior, anhedonia might be a trans-diagnostic dimension to target for suicide prevention. Methods For this 3-year-long prospective study, 2,839 outpatients with mood disorders were recruited. They were divided in: (a) two groups according to the occurrence or not of suicidal ideation during the follow-up, and (b) two groups according to the occurrence or not of suicide attempts during the follow-up. Anhedonia was assessed using a composite score (the French version of the 14-item Snaith-Hamilton Pleasure Scale and item 13 of the Quick Inventory of Depressive Symptomatology scale) at inclusion and at 6, 12, 24, and 36 months after inclusion. Results Patients with mood disorders and anhedonia at least at one follow-up visit had a 1.4-fold higher risk of suicidal ideation (adjusted odds ratio = 1.35; 95% confidence interval [1.07, 1.70]), even after adjustment for confounding factors of suicide risk (i.e., bipolar or unipolar disorder, sex, age, marital status, education level, antidepressant intake, personal history of suicide attempt, at least one childhood trauma, and mean of the maximum depression score during the follow-up). Conversely, association between anhedonia and suicide attempt did not remain significant after adjustment. Conclusions The significant association between anhedonia and suicide ideation in patients with mood disorders stresses the need of targeting hedonia in mood disorders, and of research focusing on the position to pleasure in life through eudaimonia.
نوع الوثيقة: article in journal/newspaper
اللغة: English
Relation: Depression and Anxiety; Depress Anxiety; http://hdl.handle.net/20.500.12210/110568
الاتاحة: https://hdl.handle.net/20.500.12210/110568
رقم الانضمام: edsbas.C77EEE88
قاعدة البيانات: BASE