Analysis of PINK1 –Parkin signalling pathway in lymphoblastoid cell lines and CD3/CD28 activated PBMCs.

التفاصيل البيبلوغرافية
العنوان: Analysis of PINK1 –Parkin signalling pathway in lymphoblastoid cell lines and CD3/CD28 activated PBMCs.
المؤلفون: Aaron V. Bradshaw (11681739), Philip Campbell (9388052), Anthony H. V. Schapira (9292344), Huw R. Morris (11681742), Jan-Willem Taanman (139411)
سنة النشر: 2021
المجموعة: Smithsonian Institution: Digital Repository
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Virology, screen idiopathic patients, sy5y neuroblastoma cells, cells could serve, potential mitophagy defects, pink1 &# 8212, div >< p, jurkat leukaemic cells, ubiquitinated mfn proteins, mitofusin proteins mfn1, protein expression levels, fibroblast cells, parkin proteins, comparable levels, western blotting, suitable biosample, remarkably low, readily detectable
الوصف: (A) Phase contrast microscopy images of Jurkat cells, a lymphoblastoid cell line (LCL) and CD3/CD28 Dynabead-activated PBMCs. (B) Western blot analysis of MFN1 and -2 ubiquitination following CCCP treatment of activated PBMCs and LCLs. (C) Western blot analysis of PINK1 expression in activated PBMCs and LCLs following prolonged CCCP treatment. (D) Western blot analysis of Parkin expression in resting and CD3/CD28 Dynabead-activated PBMCs, and LCLs.
نوع الوثيقة: still image
اللغة: unknown
Relation: https://figshare.com/articles/figure/Analysis_of_PINK1_Parkin_signalling_pathway_in_lymphoblastoid_cell_lines_and_CD3_CD28_activated_PBMCs_/16990665
DOI: 10.1371/journal.pone.0259903.g008
الاتاحة: https://doi.org/10.1371/journal.pone.0259903.g008
Rights: CC BY 4.0
رقم الانضمام: edsbas.C762AB7E
قاعدة البيانات: BASE
الوصف
DOI:10.1371/journal.pone.0259903.g008