Academic Journal

The Potential of Self-Assessment and Associated Factors for Delayed Symptomatic Hyponatremia Following Transsphenoidal Surgery: A Single Center Experience

التفاصيل البيبلوغرافية
العنوان: The Potential of Self-Assessment and Associated Factors for Delayed Symptomatic Hyponatremia Following Transsphenoidal Surgery: A Single Center Experience
المؤلفون: Pia Roser, Klaus Christian Mende, Georgios K. Dimitriadis, Marius Marc-Daniel Mader, Jens Aberle, Jörg Flitsch, Roman Rotermund
المصدر: Journal of Clinical Medicine; Volume 12; Issue 1; Pages: 306
بيانات النشر: Multidisciplinary Digital Publishing Institute
سنة النشر: 2022
المجموعة: MDPI Open Access Publishing
مصطلحات موضوعية: self-assessment, hyponatremia, pituitary, transsphenoidal surgery, SIADH
الوصف: (1) Background: We identified screening parameters and associated factors for delayed, symptomatic hyponatremia (DSH) following inpatient discharge after transsphenoidal surgery (TSS). (2) Methods: In this prospective, monocentric study, 108 patients who underwent TSS for pituitary pathologies were included, provided with a questionnaire and instructed to document urine specific gravity, fluid intake/urine output, body weight and clinical symptoms for every of five days following discharge from hospital. (3) Results: The overall incidence of DSH within 14 days following discharge from the hospital was 14.8% (n = 9). Symptomatic patients presented on average 8.6 days after surgery. Mild DSH was present in 3.3% of the patients, moderate in 1.6% and severe hyponatremia in 9.8% of patients. Female sex (p = 0.02) and lower BMI (p = 0.02), as well as nausea (66.7%; p < 0.01) and emesis (33.3%; p < 0.05), were associated with DSH. A significant weight delta between morning and afternoon weight two days before the event of DSH between both groups (1.26 kg (n = 5) vs. 0.79 kg (n = 52), p < 0.05) was detected. (4) Conclusions: Handing out a symptom questionnaire at discharge seems to be an easy and feasible tool for the detection of DSH after hospital discharge.
نوع الوثيقة: text
وصف الملف: application/pdf
اللغة: English
Relation: Endocrinology & Metabolism; https://dx.doi.org/10.3390/jcm12010306
DOI: 10.3390/jcm12010306
الاتاحة: https://doi.org/10.3390/jcm12010306
Rights: https://creativecommons.org/licenses/by/4.0/
رقم الانضمام: edsbas.C6F85AF8
قاعدة البيانات: BASE