Academic Journal
Risk factors for primary open angle glaucoma (POAG) progression: A study ruled in Torino
| العنوان: | Risk factors for primary open angle glaucoma (POAG) progression: A study ruled in Torino |
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| المؤلفون: | ACTIS, ALESSANDRO GUIDO, VERSINO, Elisabetta, BROGLIATTI, Beatrice, ROLLE, Teresa |
| المساهمون: | Actis, A.G, Versino, E., Brogliatti, B., Rolle, T. |
| سنة النشر: | 2016 |
| المجموعة: | Università degli studi di Torino: AperTo (Archivio Istituzionale ad Accesso Aperto) |
| مصطلحات موضوعية: | Epidemiology, Glaucoma, Intraocular pressure (IOP), Optic nerve, Progression, Risk factor, Visual field, Ophthalmology |
| الوصف: | PURPOSE: Aim of this retrospective, observational study is to describe features of a population sample, affected by primary open angle glaucoma (POAG) in order to evaluate damage progression on the basis of the emerged individual risk factors. METHODS: We included 190 caucasian patients (377 eyes), evaluating relationship between individual risk factors (explicative variables) and MD (Mean Deviation) of standard automated perimetry. We also considered the dependent variable NFI (Neural Fiber Index) of GDx scanning laser polarimetry. Progression has been evaluated through a statistic General Linear Model on four follow up steps (mean follow up 79 months). RESULTS: Factors reaching statistical significance, determining a worsening of the MD variable, are: age (P<0.0001), intraocular pressure (IOP) at follow up (P < 0.0001), female gender (P<0.0001), hypertension (P< 0.0001) and familiarity (P = 0.0006). Factors reaching statistical significance, determining a worsening of the NFI variable, are only IOP at follow up (P = 0.0159) and depression (P = 0.0104). CONCLUSION: Results of this study confirm and enforce data coming from most recent studies: IOP remains the main risk factor for glaucoma assess and progression; age and familiarity are great risk factors as underlined in the last decades; female sex can be an important risk factors as emerged only in the last years; arterial hypertension should always be evaluated in timing of our clinic follow up. KEYWORDS: Epidemiology; glaucoma; intraocular pressure (IOP); optic nerve; progression; risk factors; visual field |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/27347249; info:eu-repo/semantics/altIdentifier/wos/WOS:000424587000012; volume:10; issue:1; firstpage:129; lastpage:139; numberofpages:11; journal:THE OPEN OPHTHALMOLOGY JOURNAL; http://hdl.handle.net/2318/1604018; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84971654760; http://bentham.org/open/toophtj/ |
| DOI: | 10.2174/1874364101610010129 |
| الاتاحة: | http://hdl.handle.net/2318/1604018 https://doi.org/10.2174/1874364101610010129 http://bentham.org/open/toophtj/ |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.C65DB1AB |
| قاعدة البيانات: | BASE |
| DOI: | 10.2174/1874364101610010129 |
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