Patent
Methods of cell selection and modifying cell metabolism
| العنوان: | Methods of cell selection and modifying cell metabolism |
|---|---|
| المؤلفون: | Young, Robert, Smales, Christopher Mark, Jaques, Colin Mark, Racher, Andrew J., Singh, Gurdeep, Budge, James, Robool, Joanne |
| سنة النشر: | 2019 |
| المجموعة: | University of Kent: KAR - Kent Academic Repository |
| مصطلحات موضوعية: | Q Science |
| الوصف: | Described herein are compositions and methods for identifying, selecting, or culturing cells comprising a subject nucleic acid sequence of interest. Generally, a nucleic acid comprising a subject nucleic acid and a sequence encoding an enzyme molecule involved in biosynthesis of an amino acid is introduced into a cell. The cell is then grown on media lacking the amino acid, such that cells comprising the introduced nucleic acid are capable of growth. In some instances, the cell further comprises an inhibitor of the enzyme molecule to increase the stringency of the selection. |
| نوع الوثيقة: | patent |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | https://kar.kent.ac.uk/85782/1/WO2019152876A2.pdf; Lonza Inc (2019) Methods of cell selection and modifying cell metabolism. WO2019152876A2. (doi:WO2019152876A2) (KAR id:85782 ) |
| الاتاحة: | https://kar.kent.ac.uk/85782/ https://kar.kent.ac.uk/85782/1/WO2019152876A2.pdf https://doi.org/WO2019152876A2 |
| Rights: | cc_by_nc_nd |
| رقم الانضمام: | edsbas.C6507DAC |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |