Academic Journal
Characterization and Antimicrobial Activity of Alkaloid Extracts from Seeds of Different Genotypes of Lupinus spp.
العنوان: | Characterization and Antimicrobial Activity of Alkaloid Extracts from Seeds of Different Genotypes of Lupinus spp. |
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المؤلفون: | Flora Valeria Romeo, Simona Fabroni, Gabriele Ballistreri, Serena Muccilli, Alfio Spina, Paolo Rapisarda |
المصدر: | Sustainability, Vol 10, Iss 3, p 788 (2018) |
بيانات النشر: | MDPI AG |
سنة النشر: | 2018 |
المجموعة: | Directory of Open Access Journals: DOAJ Articles |
مصطلحات موضوعية: | alkaloids, antimicrobial activity, germplasm, Klebsiella, landraces, lupanine, Pseudomonas, varieties, Environmental effects of industries and plants, TD194-195, Renewable energy sources, TJ807-830, Environmental sciences, GE1-350 |
الوصف: | Alkaloid profiles of 22 lupin genotypes belonging to three different cultivated species, Lupinus albus L., Lupinus luteus L., and Lupinus angustifolius L., collected from different Italian regions and grown in Sicily, were studied by gas chromatography mass spectrometry (GC-MS) to determine alkaloid composition. More than 30 alkaloids were identified. The lowest alkaloid concentration was observed in the L. albus Luxor, Aster, and Rosetta cultivars, and in all the varieties of L. luteus and L. angustifolius. The highest content was observed in all the landraces of L. albus. Surprisingly, the white lupin Lublanc variety and the commercial seeds of cv Multitalia had a high alkaloid content. The tested species and the different genotypes exhibited different alkaloid profiles: lupanine, 13α-hydroxylupanine, and albine were the main alkaloids in the analyzed L. albus seeds; angustifoline and 13α-tigloyloxylupanine were well-represented in L. albus landraces; sparteine and lupinine were typical of L. luteus; and lupanine, 13α-hydroxylupanine, and angustifoline were the main alkaloids in L. angustifolius seeds. The samples with the highest amounts of total alkaloids proved to be interesting from a pharmaceutical viewpoint. The alkaloid extracts showed significant activity on Klebsiella pneumoniae and Pseudomonas aeruginosa clinical isolates. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 2071-1050 |
Relation: | http://www.mdpi.com/2071-1050/10/3/788; https://doaj.org/toc/2071-1050; https://doaj.org/article/e4f1a77af5f1483b94adf7ef5c46349b |
DOI: | 10.3390/su10030788 |
الاتاحة: | https://doi.org/10.3390/su10030788 https://doaj.org/article/e4f1a77af5f1483b94adf7ef5c46349b |
رقم الانضمام: | edsbas.C61D69E |
قاعدة البيانات: | BASE |
تدمد: | 20711050 |
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DOI: | 10.3390/su10030788 |