Academic Journal
Metastatic Prostatic Ductal Adenocarcinoma Successfully Treated with Docetaxel Chemotherapy: A Case Report
| العنوان: | Metastatic Prostatic Ductal Adenocarcinoma Successfully Treated with Docetaxel Chemotherapy: A Case Report |
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| المؤلفون: | Fujiwara, Ryo, Kageyama, Susumu, Tomita, Keiji, Hanada, Eiki, Tsuru, Teruhiko, Yoshida, Tetsuya, Narita, Mitsuhiro, Isono, Takahiro, Kawauchi, Akihiro |
| المصدر: | Case Reports in Oncology ; volume 8, issue 2, page 339-344 ; ISSN 1662-6575 |
| بيانات النشر: | S. Karger AG |
| سنة النشر: | 2015 |
| الوصف: | A 68-year-old man presented with gross hematuria. A papillary urethral tumor adjacent to the verumontanum was found by cystourethroscopy. Serum prostate-specific antigen (PSA) was 3.246 ng/ml. A transurethral biopsy specimen was most suggestive of a primary urothelial carcinoma of the prostate, for which a radical cystoprostatectomy was performed. The final pathology was prostatic ductal adenocarcinoma with very focal acinar features (Gleason score 5 + 4 = 9, pT3bN0M0). Local recurrence and pelvic bone metastases developed 17 months later, and his PSA rose to 10.806 ng/ml. He was treated with combined androgen blockade and radiation. Two years later, the lesion showed progressive growth. Treatment followed with docetaxel (70 mg/m 2 every 3 weeks) and prednisolone 5 mg twice daily. After 10 cycles of chemotherapy, all lesions disappeared and PSA decreased to <0.005 ng/ml. Three years after chemotherapy, he maintains a complete response without any additional treatments. Docetaxel chemotherapy can be an effective treatment for patients with recurrent prostatic ductal adenocarcinoma. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1159/000438785 |
| الاتاحة: | http://dx.doi.org/10.1159/000438785 https://www.karger.com/Article/Pdf/438785 |
| Rights: | https://creativecommons.org/licenses/by-nc/3.0/ ; https://creativecommons.org/licenses/by-nc/3.0/ |
| رقم الانضمام: | edsbas.C5760146 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1159/000438785 |
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