التفاصيل البيبلوغرافية
| العنوان: |
AExaCTT - Aerobic Exercise and Consecutive Task-specific Training for the upper limb after stroke: protocol for a randomised controlled pilot study |
| المؤلفون: |
Valkenborghs, Sarah R., Visser, Milanka M., Dunn, Ashlee, Erickson, Kirk I., Nilsson, Michael, Callister, Robin, van Vliet, Paulette |
| المساهمون: |
The University of Newcastle. Faculty of Health & Medicine, Priority Research Centre for Physical Activity and Nutrition |
| بيانات النشر: |
Elsevier |
| سنة النشر: |
2017 |
| المجموعة: |
NOVA: The University of Newcastle Research Online (Australia) |
| مصطلحات موضوعية: |
stroke, motor function, aerobic exercise, task-specific training |
| الوصف: |
Motor function may be enhanced if aerobic exercise is paired with motor training. One potential mechanism is that aerobic exercise increases levels of brain-derived neurotrophic factor (BDNF), which is important in neuroplasticity and involved in motor learning and motor memory consolidation. This study will examine the feasibility of a parallel-group assessor-blinded randomised controlled trial investigating whether task-specific training preceded by aerobic exercise improves upper limb function more than task-specific training alone, and determine the effect size of changes in primary outcome measures. People with upper limb motor dysfunction after stroke will be allocated to either task-specific training or aerobic exercise and consecutive task-specific training. Both groups will perform 60 hours of task-specific training over 10 weeks, comprised of 3 × 1 hour sessions per week with a therapist and 3 × 1 hours of home-based self-practice per week. The combined intervention group will also perform 30 minutes of aerobic exercise (70-85% HR max ) immediately prior to the 1 hour of task-specific training with the therapist. Recruitment, adherence, retention, participant acceptability, and adverse events will be recorded. Clinical outcome measures will be performed pre-randomisation at baseline, at completion of the training program, and at 1 and 6 months follow-up. Primary clinical outcome measures will be the Action Research Arm Test (ARAT) and the Wolf Motor Function Test (WMFT). If aerobic exercise prior to task-specific training is acceptable, and a future phase 3 randomised controlled trial seems feasible, it should be pursued to determine the efficacy of this combined intervention for people after stroke. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| تدمد: |
2451-8654 |
| Relation: |
Contemporary Clinical Trials Communications Vol. 7, Issue September 2017, p. 179-185; http://hdl.handle.net/1959.13/1350588; uon:30579 |
| الاتاحة: |
http://hdl.handle.net/1959.13/1350588 |
| Rights: |
© 2017 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/) |
| رقم الانضمام: |
edsbas.C55E48FA |
| قاعدة البيانات: |
BASE |
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