Academic Journal
ST peak during percutaneous coronary intervention serves as an early prognostic predictor in patients with ST-segment elevation myocardial
| العنوان: | ST peak during percutaneous coronary intervention serves as an early prognostic predictor in patients with ST-segment elevation myocardial |
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| المؤلفون: | Lønborg, Jacob, Kelbæk, Henning, Engstrøm, Thomas, Helqvist, Steffen, Kløvgaard, Lene, Holmvang, Lene, Vejlstrup, Niels, Jørgensen, Erik, Saunamäki, Kari, Dridi, Nadia P, Kaltoft, Anne, Bøtker, Hans-Erik, Clemmensen, Peter, Terkelsen, Christian Juhl |
| المصدر: | Lønborg , J , Kelbæk , H , Engstrøm , T , Helqvist , S , Kløvgaard , L , Holmvang , L , Vejlstrup , N , Jørgensen , E , Saunamäki , K , Dridi , N P , Kaltoft , A , Bøtker , H-E , Clemmensen , P & Terkelsen , C J 2014 , ' ST peak during percutaneous coronary intervention serves as an early prognostic predictor in patients with ST-segment elevation myocardial ' , EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of .... |
| سنة النشر: | 2014 |
| المجموعة: | Aarhus University: Research |
| الوصف: | AIMS: To evaluate the clinical importance of the ST peak phenomenon during primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI). METHODS AND RESULTS: Continuous ST monitoring was performed in 942 STEMI patients from arrival until 90 minutes after revascularisation. ST peak was defined as ≥1 mm increase in the ST-segment during PCI compared with the ST elevation before intervention. ST peak was observed in 26.9% of patients. During median follow-up of 4.1 years, 20.7% of patients experienced a major adverse cardiac event (MACE). ST peak was associated with higher rates of mortality (13.4% versus 9.3%; p=0.044), admission for heart failure (10.6% versus 5.2%; p=0.002) and MACE (26.9% versus 18.2%; p=0.002), but not reinfarction (7.1% versus 5.2%; p=0.14). In two different Cox regression analyses, adjusting for predictors of MACE and ST peak including ST resolution and epicardial flow, ST peak remained significantly associated with MACE: adjusted hazard ratio (HR) 1.40 (95% confidence interval [CI] 1.01-1.95) and 1.41 (95% CI: 1.02-1.96). CONCLUSIONS: In the largest study hitherto evaluating the ST peak phenomenon during primary PCI, we demonstrated that ST peak is a strong predictor of adverse long-term outcome and provides independent prognostic information beyond that provided by ST resolution and epicardial flow. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.4244/EIJV10I4A80 |
| الاتاحة: | https://pure.au.dk/portal/en/publications/217d13d2-559d-45d4-a59d-e845d5f1ccc6 https://doi.org/10.4244/EIJV10I4A80 |
| Rights: | info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: | edsbas.C523DB |
| قاعدة البيانات: | BASE |
| DOI: | 10.4244/EIJV10I4A80 |
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