Academic Journal
Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension
| العنوان: | Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension |
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| المؤلفون: | Özer, Savaş, Yücekal, Burcu, Yücel, Ahmet Seyda, Özyıldız, Ali Gökhan, Kınık, Mustafa, Turan, Oğuzhan Ekrem, Aslan, Mehmet Gökhan, Çetin, Mustafa |
| المساهمون: | RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Özer, Savaş, Yılmaz, Ahmet Seyda, Özyıldız, Ali Gökhan, Kınık, Mustafa, Aslan, Mehmet Gökhan, Çetin, Mustafa |
| بيانات النشر: | Kare Publishing |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Epicardial adipose tissue thickness, Hypertension, Retinopathy |
| الوصف: | OBJECTIVE: Hypertensive retinopathy develops based on endothelial dysfunction, inflammation, and atherosclerosis. Epicardial fat secretes various cytokines associated with endothelial dysfunction, oxidative stress, inflammation, and atherosclerosis. We aimed to evaluate whether epicardial adipose tissue (EAT) thickness is a marker for retinopathy in newly diagnosed hypertensive patients. METHODS: A total of 73 newly diagnosed hypertension (HT) patients were included in the study. Transthoracic echocardiography (TTE) was used to measure EAT thickness. To evaluate the presence of retinopathy in HT patients, hypertensive retinopathy staging was performed by ophthalmologists, according to Scheie classification. RESULTS: Retinopathy was detected in 27 (37.0%) of 73 patients. EAT thickness in HT patients with retinopathy was higher than the group without retinopathy (5.07 +/- 1.45 mm vs. 4.19 +/- 1.20 mm, p=0.007). Low-density lipoprotein cholesterol (LDL-C) levels in HT patients with retinopathy were higher than the group without retinopathy (162.4 +/- 41.2 mg/dl vs. 138.1 +/- 35.6 mg/dl, p=0.010). As a result of the regression analysis, LDL-C (OR=1.016, 95% CI 1.001-1.031, p=0.043) and EAT thickness (OR=1.674, 95% CI 1.069-2.626, p=0.043) were the independent predictors of retinopathy. CONCLUSION: Increased EAT thickness is associated with the presence of retinopathy in hypertensive patients. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2148-4902 |
| Relation: | Northern Clinics of İstanbul; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; Ozer, S., Yucekul, B., Yilmaz, A. S., Ozyildiz, A. G., Kinik, M., Turan, O. E., Aslan, M. G., & Cetin, M. (2021). Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension. Northern clinics of Istanbul, 8(4), 365–370. https://doi.org/10.14744/nci.2020.23334; https://doi.org/10.14744/nci.2020.23334; https://hdl.handle.net/11436/6308; 365; 370 |
| DOI: | 10.14744/nci.2020.23334 |
| الاتاحة: | https://hdl.handle.net/11436/6308 https://doi.org/10.14744/nci.2020.23334 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.C3C92A73 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 21484902 |
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| DOI: | 10.14744/nci.2020.23334 |