Academic Journal
Validation of Heel Stick Microsampling To Optimize Micafungin Doses in Neonates and Young Infants
| العنوان: | Validation of Heel Stick Microsampling To Optimize Micafungin Doses in Neonates and Young Infants |
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| المؤلفون: | Auriti, Cinzia, Goffredo, Bianca Maria, Ronchetti, Maria Paola, Piersigilli, Fiammetta, Cairoli, Sara, Bersani, Iliana, Dotta, Andrea, Pai, Manjunath P. |
| المساهمون: | Astellas Pharma Europe |
| المصدر: | Antimicrobial Agents and Chemotherapy ; volume 62, issue 10 ; ISSN 0066-4804 1098-6596 |
| بيانات النشر: | American Society for Microbiology |
| سنة النشر: | 2018 |
| الوصف: | Major gaps exist in our knowledge of antimicrobial pharmacokinetics in critically ill neonates and infants that require validated microsampling and bioanalysis methods to support therapeutic drug monitoring. We compared serially collected intravenous (i.v.) and heel stick capillary (HSC)-sampled plasma concentrations of micafungin (8 mg/kg) in eight infants born preterm with systemic candidiasis. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1128/aac.01199-18 |
| DOI: | 10.1128/AAC.01199-18 |
| الاتاحة: | http://dx.doi.org/10.1128/aac.01199-18 https://journals.asm.org/doi/pdf/10.1128/AAC.01199-18 |
| Rights: | https://journals.asm.org/non-commercial-tdm-license |
| رقم الانضمام: | edsbas.C34A6BF9 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1128/aac.01199-18 |
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