Academic Journal
The Wood equation allows consistent fitting of individual antibody-response profiles of Zika virus or SARS-CoV-2 infected patients
العنوان: | The Wood equation allows consistent fitting of individual antibody-response profiles of Zika virus or SARS-CoV-2 infected patients |
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المؤلفون: | Denis, J, Garnier, A, Claverie, D, de Laval, F, Attoumani, S, Tenebray, B, Durand, G, A, Coutard, B, Leparc-Goffart, I, Tournier, Jean-Nicolas, Briolant, S, Badaut, C |
المساهمون: | Institut de Recherche Biomédicale des Armées Brétigny-sur-Orge (IRBA), Centre National de Référence (CNR) des Arbovirus - Laboratoire coordonnateur : Equipe Résidente de Recherche d'Infectiologie Tropicale (ERRIT), Institut de Recherche Biomédicale des Armées Hôpital d’Instruction des Armées Laveran, Centre d'épidémiologie et de santé publique des armées Marseille (CESPA), Service de Santé des Armées, Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Unité des Virus Emergents (UVE), Institut de Recherche Biomédicale des Armées Antenne Marseille (IRBA), Laboratoire d’innovation : vaccins – Innovation lab : vaccines, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), École du Val de Grâce (EVDG), Vecteurs - Infections tropicales et méditerranéennes (VITROME), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées Brétigny-sur-Orge (IRBA), This work was partially supported by the European Union’s Horizon H2020 Project “Advanced Nanosensing platforms for Point ofcare global diagnostics and surveillance” (CONVAT) (No 101003544) and partially funded by the Direction Générale de l’Armementand the Service de Santé des Armées (Biomedef PDH-2-NRBC-2-B-2111), and the Direction centrale du Service de santé des armées(grant IDs: 2016RC10). |
المصدر: | ISSN: 2405-8440 ; Heliyon ; https://inserm.hal.science/inserm-04542744 ; Heliyon, 2023, 9 (11), pp.e21945. ⟨10.1016/j.heliyon.2023.e21945⟩. |
بيانات النشر: | HAL CCSD Elsevier |
سنة النشر: | 2023 |
مصطلحات موضوعية: | Curve fit, Humoral immune response, Kinetic, SARS-CoV-2, Wood equation, Zika virus, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie |
الوصف: | International audience ; Antibody kinetic curves obtained during a viral infection are often fitted using aggregated patient data, hiding the heterogeneity of individual humoral immune responses. Individual antibody responses can be modeled using the Wood equation and grouped according to their profile. Such modeling takes into account several important kinetic parameters, such as the day when antibody detection becomes positive [daypos], the day of the maximal response [daymax], the maximum antibody level [levelmax], and the day when antibody detection becomes negative [dayneg]. Potential associations between these profiles and studied factors can then be tested. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
Relation: | info:eu-repo/semantics/altIdentifier/pmid/38027965; inserm-04542744; https://inserm.hal.science/inserm-04542744; https://inserm.hal.science/inserm-04542744/document; https://inserm.hal.science/inserm-04542744/file/PIIS2405844023091533.pdf; PUBMED: 38027965; PUBMEDCENTRAL: PMC10658335 |
DOI: | 10.1016/j.heliyon.2023.e21945 |
الاتاحة: | https://inserm.hal.science/inserm-04542744 https://inserm.hal.science/inserm-04542744/document https://inserm.hal.science/inserm-04542744/file/PIIS2405844023091533.pdf https://doi.org/10.1016/j.heliyon.2023.e21945 |
Rights: | http://creativecommons.org/licenses/by-nc-nd/ ; info:eu-repo/semantics/OpenAccess |
رقم الانضمام: | edsbas.C292FD46 |
قاعدة البيانات: | BASE |
DOI: | 10.1016/j.heliyon.2023.e21945 |
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