Academic Journal
Priority effects shape the structure of infant-type Bifidobacterium communities on human milk oligosaccharides
| العنوان: | Priority effects shape the structure of infant-type Bifidobacterium communities on human milk oligosaccharides |
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| المؤلفون: | Ojima, Miriam N., Jiang, Lin, Arzamasov, Aleksandr A., Yoshida, Keisuke, Odamaki, Toshitaka, Xiao, Jinzhong, Nakajima, Aruto, Kitaoka, Motomitsu, Hirose, Junko, Urashima, Tadasu, Katoh, Toshihiko, Gotoh, Aina, van Sinderen, Douwe, Rodionov, Dmitry A., Osterman, Andrei L., Sakanaka, Mikiyasu, Katayama, Takane |
| المساهمون: | 尾島, 望美, 吉田, 圭佑, 小田巻, 俊孝, 肖, 金忠, 中島, 有登, 北岡, 本光, 廣瀬, 潤子, 浦島, 匡, 加藤, 紀彦, 後藤, 愛那, 阪中, 幹祥, 片山, 高嶺, 40724612, 60801892, 70346104 |
| بيانات النشر: | Springer Nature |
| سنة النشر: | 2022 |
| المجموعة: | Kyoto University Research Information Repository (KURENAI) / 京都大学学術情報リポジトリ |
| مصطلحات موضوعية: | Community ecology, Microbial ecology, Microbiome |
| الوصف: | 母乳栄養児の腸内におけるビフィズス菌コミュニティー形成には先住効果が大きな影響を及ぼす --ヒトミルクオリゴ糖利用能力の低いビフィズス菌B. breveが優勢となる仕組み--. 京都大学プレスリリース. 2022-07-27. ; Bifidobacteria are among the first colonizers of the infant gut, and human milk oligosaccharides (HMOs) in breastmilk are instrumental for the formation of a bifidobacteria-rich microbiota. However, little is known about the assembly of bifidobacterial communities. Here, by applying assembly theory to a community of four representative infant-gut associated Bifidobacterium species that employ varied strategies for HMO consumption, we show that arrival order and sugar consumption phenotypes significantly affected community formation. Bifidobacterium bifidum and Bifidobacterium longum subsp. infantis, two avid HMO consumers, dominate through inhibitory priority effects. On the other hand, Bifidobacterium breve, a species with limited HMO-utilization ability, can benefit from facilitative priority effects and dominates by utilizing fucose, an HMO degradant not utilized by the other bifidobacterial species. Analysis of publicly available breastfed infant faecal metagenome data showed that the observed trends for B. breve were consistent with our in vitro data, suggesting that priority effects may have contributed to its dominance. Our study highlights the importance and history dependency of initial community assembly and its implications for the maturation trajectory of the infant gut microbiota. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1751-7362 1751-7370 |
| Relation: | https://www.kyoto-u.ac.jp/ja/research-news/2022-07-27-2; http://hdl.handle.net/2433/275900; The ISME Journal; 16; 2265; 2279 |
| الاتاحة: | http://hdl.handle.net/2433/275900 |
| Rights: | © The Author(s) 2022 ; This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. ; http://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: | edsbas.C273818 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 17517362 17517370 |
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