Academic Journal
Assessment of haemostasis in pregnant women ; A retrospective evaluation of the diagnostic performance of the HEMSTOP standardised questionnaire
| العنوان: | Assessment of haemostasis in pregnant women ; A retrospective evaluation of the diagnostic performance of the HEMSTOP standardised questionnaire |
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| المؤلفون: | Zec, Tamara, Schmartz, Denis, Temmerman, Pomeline, Fils, Jean-François, Ickx, Brigitte, Bonhomme, Fanny, Van Der Linden, Philippe |
| المصدر: | European Journal of Anaesthesiology Intensive Care ; volume 3, issue 2, page e0050 ; ISSN 2767-7206 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health) |
| سنة النشر: | 2024 |
| الوصف: | BACKGROUND Contemporary guidelines pertaining to the evaluation of bleeding risk recommend conducting a comprehensive examination of both personal and family histories concerning haemorrhagic diatheses. OBJECTIVES We employed the standardised HEMSTOP (Hematoma, hEmorrhage, Menorrhagia, Surgery, Tooth extraction, Obstetrics, Parents) questionnaire in pregnant women to evaluate its efficacy in detecting a haemostatic disorder and predicting the risk of haemorrhage associated with delivery. DESIGN A single-centre retrospective observational cohort study. SETTING Brugmann Hospital, a tertiary university institution. PATIENTS All full-term parturients who underwent vaginal or caesarean delivery in our hospital between January 2020 and December 2021 were included in the study. A total of 3588 patients were enrolled. MAIN OUTCOME MEASURES The primary aim of this study was to assess the sensitivity and specificity of the HEMSTOP questionnaire in identifying individuals with an abnormal primary haemostatic profile. The secondary objective was to evaluate the sensitivity and specificity of the HEMSTOP questionnaire in predicting postpartum haemorrhage (PPH; defined as blood loss >1000 ml). Additionally, positive-predictive values and negative-predictive values (NPVs) were calculated. RESULTS The specificity and sensitivity of the HEMSTOP questionnaire to predict an abnormal standard coagulation test in pregnant women are respectively 96% [95% confidence interval (CI), 0.95 to 0.97] and 39% (95% CI, 0.20 to 0.61). Its NPV is 100%. The specificity and sensitivity of the HEMSTOP questionnaire to predict postpartum bleeding risk are respectively 96% (95% CI, 0.95 to 0.97) and 8% (95% CI, 0.06 to 0.11). CONCLUSION In the conditions of our study, the HEMSTOP questionnaire enables the prediction of a primary haemostatic anomaly with a specificity and sensitivity comparable to routine haemostatic assessments. These findings concur with the recommendation against the routine prescription of laboratory tests for patients lacking ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1097/ea9.0000000000000050 |
| DOI: | 10.1097/EA9.0000000000000050 |
| الاتاحة: | http://dx.doi.org/10.1097/ea9.0000000000000050 https://journals.lww.com/10.1097/EA9.0000000000000050 |
| Rights: | http://creativecommons.org/licenses/by/4.0 |
| رقم الانضمام: | edsbas.C26BE221 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1097/ea9.0000000000000050 |
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