Academic Journal
Laminin promotes cerebellar granule cells migration in vitro and is synthesized by cultured astrocytes
| العنوان: | Laminin promotes cerebellar granule cells migration in vitro and is synthesized by cultured astrocytes |
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| المؤلفون: | SELAK, Ivan, Foidart, Jean-Michel, Moonen, Gustave |
| المصدر: | Developmental Neuroscience, 7 (5-6), 278-285 (1985) |
| بيانات النشر: | Karger |
| سنة النشر: | 1985 |
| المجموعة: | University of Liège: ORBi (Open Repository and Bibliography) |
| مصطلحات موضوعية: | Life sciences, Biochemistry, biophysics & molecular biology, Human health sciences, Neurology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire, Sciences de la santé humaine, Neurologie |
| الوصف: | peer reviewed ; Newborn rat cerebellum microexplants have been used as a model to study neuronal migration. Laminin in a substrate-bound form modifies extensively the migratory behavior of the neurones, an effect which is blocked if antilaminin antibodies are present during the assay. 35S methionine incorporation followed by SDS-PAGE electrophoresis, fluorography and immunoprecipitation with antilaminin antibodies allowed to demonstrate that laminin is synthesized and secreted by cultured newborn rat cerebellum as well as by cultured newborn rat cerebral cortex astrocytes. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0378-5866 1421-9859 |
| Relation: | urn:issn:0378-5866; urn:issn:1421-9859; https://orbi.uliege.be/handle/2268/87657; info:hdl:2268/87657; info:pmid:3836139 |
| DOI: | 10.1159/000112296 |
| الاتاحة: | https://orbi.uliege.be/handle/2268/87657 https://doi.org/10.1159/000112296 |
| رقم الانضمام: | edsbas.C267E1DA |
| قاعدة البيانات: | BASE |
| تدمد: | 03785866 14219859 |
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| DOI: | 10.1159/000112296 |