Academic Journal
Determination of the Wound Healing Potentials of Medicinal Plants Historically Used in Ghana
| العنوان: | Determination of the Wound Healing Potentials of Medicinal Plants Historically Used in Ghana |
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| المؤلفون: | Sara H. Freiesleben, Jens Soelberg, Nils T. Nyberg, Anna K. Jäger |
| المصدر: | Evidence-Based Complementary and Alternative Medicine, Vol 2017 (2017) |
| بيانات النشر: | Hindawi Limited |
| سنة النشر: | 2017 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Other systems of medicine, RZ201-999 |
| الوصف: | The present study was carried out to investigate the wound healing potentials of 17 medicinal plants historically used in Ghana for wound healing. Warm and cold water extracts were prepared from the 17 dried plant species and tested in vitro in the scratch assay with NIH 3T3 fibroblasts from mice. The wound healing scratch assay was used to evaluate the effect of the plants on cell proliferation and/or migration in vitro, as a test for potential wound healing properties. After 21 hours of incubation increased proliferation and/or migration of fibroblasts in the scratch assay was obtained for 5 out of the 17 plant species. HPLC separation of the most active plant extract, which was a warm water extract of Philenoptera cyanescens, revealed the wound healing activity to be attributed to rutin and a triglycoside of quercetin. The present study suggests that Allophylus spicatus, Philenoptera cyanescens, Melanthera scandens, Ocimum gratissimum, and Jasminum dichotomum have wound healing activity in vitro. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1741-427X 1741-4288 |
| Relation: | http://dx.doi.org/10.1155/2017/9480791; https://doaj.org/toc/1741-427X; https://doaj.org/toc/1741-4288; https://doaj.org/article/2e7c8bc206204dae9cc6428845c872b4 |
| DOI: | 10.1155/2017/9480791 |
| الاتاحة: | https://doi.org/10.1155/2017/9480791 https://doaj.org/article/2e7c8bc206204dae9cc6428845c872b4 |
| رقم الانضمام: | edsbas.C22ECF00 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 1741427X 17414288 |
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| DOI: | 10.1155/2017/9480791 |