التفاصيل البيبلوغرافية
| العنوان: |
Risk factors for early and late mortality after fenestrated and branched endovascular repair of complex aneurysms |
| المؤلفون: |
Van Calster, Katrien, Bianchini, Aurelia, Elias, Fadi, Hertault, Adrien, Azzaoui, Richard, Fabre, Dominique, Sobocinski, Jonathan, Haulon, Stephan |
| المساهمون: |
CHU Lille, Inserm, Université de Lille, Centre Hospitalier Régional Universitaire CHU Lille CHRU Lille, McMaster University Hamilton, Ontario, Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 MBLC - ADDS, Pôle des Cardiopathies Congénitales du Nouveau-Né à L'adulte - Centre Constitutif Cardiopathies Congénitales Complexes M3C, Groupe Hospitalier Paris Saint-Joseph, Hôpital Marie-Lannelongue, Inserm U999, Université Paris-Saclay, Advanced Drug Delivery Systems (ADDS) - U1008 |
| سنة النشر: |
2024 |
| المجموعة: |
LillOA (Lille Open Archive - Université de Lille) |
| مصطلحات موضوعية: |
Aorta, Aneurysm, Endovascular repair, Fenestrated |
| الوصف: |
The objective of this study was to evaluate outcomes after fenestrated and branched endovascular aneurysm repair (F-BEVAR) performed in high-risk patients to treat pararenal (PR) aneurysms and thoracoabdominal aortic aneurysms (TAAAs) and to identify those patients likely to benefit from this treatment. A prospective single-center review of patients treated electively for PR aneurysm and TAAA using F-BEVAR between 2004 and 2016 was performed. Survival was estimated using the Kaplan-Meier method. Risk factors associated with 30-day morbidity and mortality during follow-up were determined using multivariate statistical techniques and a Cox regression model including all variables that were significant on univariate analysis (P < .05). There were 468 patients (median age, 71.6 years) identified, with American Society of Anesthesiologists score ≥3 in 94.7%. There were 221 (47.2%) type I to type III TAAAs and 247 (52.8%) type IV and type V TAAAs and PR aneurysms, with a median diameter of 58 mm. Technical success for target vessel stenting was 99.1% (1493/1506). The 30-day mortality rate was 4.9% (23 patients). The spinal cord ischemia rate was 3.8% (18 patients). Twenty patients (4.3%) required postoperative dialysis and four patients (0.8%) long-term dialysis after discharge. Median follow-up was 29 months. Survival at 1 year, 3 years, and 5 years was 86.7% (95% confidence interval [CI], 83.1-89.6), 73.3% (95% CI, 68.3-77.6), and 59.6% (95% CI, 53.4-65.2), respectively. Freedom from any target vessel occlusion and freedom from secondary procedures were 96.2% (95% CI, 93.8-97.7) and 88.2% (95% CI, 84.8-90.9) at 1 year and 90.0% (95% CI, 84.5-91.9) and 70.2% (95% CI, 63.9-75.6) at 5 years, respectively. In multivariate analysis, early mortality was associated with procedure time (hazard ratio [HR], 1.007 per minute; 95% CI, 1.003-1.010; P < .001), TAAA preoperative diameter (HR, 1.053 per millimeter; 95% CI, 1.020-1.087; P = .001), and chronic kidney disease (HR, 3.139; 95% CI, 1.369-7.196; P = .007). Mortality ... |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/octet-stream |
| اللغة: |
English |
| Relation: |
Journal of Vascular Surgery; J. Vasc. Surg.; http://hdl.handle.net/20.500.12210/37027 |
| الاتاحة: |
https://hdl.handle.net/20.500.12210/37027 |
| Rights: |
info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.C1C1E688 |
| قاعدة البيانات: |
BASE |