التفاصيل البيبلوغرافية
| العنوان: |
Evaluation of serum s100b values in high grade glioma patients [Yüksek Gradeli Gliom Hastalarında Serum S100B Değerlerinin Değerlendirilmesi Ozet] |
| المؤلفون: |
Oktay K., Olguner S.K., Sarac M.E., Özsoy K.M., Çetinalp N.E., Gezercan Y., Erman T. |
| المساهمون: |
Çukurova Üniversitesi |
| بيانات النشر: |
Ege University Press |
| سنة النشر: |
2015 |
| مصطلحات موضوعية: |
Anaplastic astrocytoma, Glioblastoma, Gliosarcoma, S100B |
| الوصف: |
Aim: Assesment of serum S100B values' additional contributions to the current scan techniques in the diagnostic and postoperative follow-up stages of high grade glial tumors and assesment of availability of serum S100B protein values as a tumor marker or a prognostic factor for the high grade glial tumors. Materials and Methods: 14 patients who were operated with high grade glial tumor diagnosis in the neurosurgery clinic and a control group consisting of 14 healthy individuals were enrolled to the study. Serum S100B protein values were measured and tumor volumes of the patients were determined with the scan techniques. Preoperative and postoperative serum S100B values were compared. Results: When serum S100B values of patient and control groups were compared, S100B values of the patient group were found significantly higher (p < 0,05). When the patients' tumor volumes and serum S100B values were compared, statistically significant relation between tumor values and serum S100B values wasn't determined (p > 0,05). But a significant reduction of S100B values was determined in the postoperative day 5 measurements of the patients in whom total resection was performed (p < 0,05). Conclusions: A significant correlation wasn't determined as the assesment of tumor volumes and serum S100B values. The rise of the serum S100B values in the high grade glioma patients was defined but a definitive conclusion wasn't determined because of the false negative values and the minority of the patient group (N=14). We think that more significant and directive conclusions shall be defined with the more comprehensive studies in the oncoming period. © 2015, Ege University Press. All rights reserved. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| تدمد: |
1300-1817 |
| Relation: |
Journal of Neurological Sciences; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://hdl.handle.net/20.500.12605/14844; 32; 738; 746 |
| الاتاحة: |
https://hdl.handle.net/20.500.12605/14844 |
| Rights: |
info:eu-repo/semantics/closedAccess |
| رقم الانضمام: |
edsbas.C0F76443 |
| قاعدة البيانات: |
BASE |