Academic Journal
Sustained seroprevalence of SARS-CoV-2 antibodies one year after infection: one of the first COVID-19 cluster cases in Bosnia and Herzegovina
| العنوان: | Sustained seroprevalence of SARS-CoV-2 antibodies one year after infection: one of the first COVID-19 cluster cases in Bosnia and Herzegovina |
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| المؤلفون: | Šušak, Božo, Mikulić, Vinka, Lazarević, Armina, Mikulić, Ivanka, Arapovic, Jurica |
| المصدر: | Bosnian Journal of Basic Medical Sciences; Vol. 22 No. 1 (2022); 147-152 ; 1840-4812 ; 1512-8601 |
| بيانات النشر: | Association of Basic Medical Sciences of FBIH |
| سنة النشر: | 2022 |
| المجموعة: | Bosnian Journal of Basic Medical Sciences (BJBMS) |
| مصطلحات موضوعية: | Bosnia and Herzegoina, pandemic, SARS-CoV-2, COVID-19, immune response, seroconversion, IgG |
| الوصف: | SARS-CoV-2 (severe acute respiratory syndrome coronavirus type 2) is a novel virus that has been identified as a causal agent of COVID-19, an emergent infectious disease which brought about a new pandemic in the twenty-first century. The immune responses and clinical features of individuals infected with SARS-CoV-2 have not yet been fully described. Thus, in this study, we compare the seroprevalence and define the correlation between symptoms and serological results in the first COVID-19 cluster in the city of Konjic, Bosnia and Herzegovina. Of the total number, 93% of RT-PCR positive participants had positive IgG serology and 75% of them developed symptoms of COVID-19. We found that there was no significant alteration in specific IgG (p = 0.504) antibody levels during the 1-year period after COVID-19. Our results indicate that symptomatic COVID-19 patients have a higher rate of seroconversion (p < 0.01). The IgG seroconversion was correlated with high fever (p = 0.002) and headache (p = 0.007), suggesting that these symptoms could be considered as indicators of a better immune response. This study has demonstrated persistence of sustained levels of specific SARS-CoV-2 antibodies after recovering from COVID-19 infection. However, in order to gain a better insight into the immune response to SARS-CoV-2, further systematic studies should be focused on quality and longevity analyses. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf; text/xml |
| اللغة: | English |
| Relation: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/6340/2354; https://www.bjbms.org/ojs/index.php/bjbms/article/view/6340/2457; https://www.bjbms.org/ojs/index.php/bjbms/article/view/6340 |
| DOI: | 10.17305/bjbms.2021.6340 |
| الاتاحة: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/6340 https://doi.org/10.17305/bjbms.2021.6340 |
| Rights: | Copyright (c) 2021 Božo Šušak, Vinka Mikulić, Armina Lazarević, Ivanka Mikulić, Jurica Arapovic ; https://creativecommons.org/licenses/by/4.0 |
| رقم الانضمام: | edsbas.C0F10568 |
| قاعدة البيانات: | BASE |
| DOI: | 10.17305/bjbms.2021.6340 |
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