Academic Journal
CKD / Clinical epidemiology
| العنوان: | CKD / Clinical epidemiology |
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| المؤلفون: | Imai, Enyu, Horio, Masaru, Yasuda, Yoshinari, Shibata, Kanakko, Imai, Junko, Kato, Tsuneko, Maruyama, Shoichi, Matsuo, Seiichi, Hermida, R.C., Otero, A., Piñeiro, L., Ayala, D.E., Moya, A., Sineiro, E., Fontao, M.J., Mojon, A., Fernandez, J.R., Investigadores Proyecto Hygia, Bernheim, Jaques, Podjarny, Eduardo, Chouraqui, Menahem, Hekselman, Igal, Goldbourt, Uri, Rayner, Hugh, Hollingworth, Lee, Higgins, Robert, Dodds, Simon, Yasuda, Keiko, Sasaki, Koichi, Hatanaka, Masaki, Obi, Yoshitsugu, Kimura, Tomonori, Hayashi, Terumasa |
| بيانات النشر: | Oxford University Press |
| سنة النشر: | 2011 |
| المجموعة: | HighWire Press (Stanford University) |
| مصطلحات موضوعية: | Friday 24 June 2011 |
| الوصف: | INTRODUCTION AND AIMS: Hypertension is the leading cause of cerebrovascular disease, congestive heart failure and chronic kidney disease. Approximately 30% of Japanese general population and more than 75% of Japanese CKD stage 3-5 has hypertension. Hypertension accelerates progression of CKD. The higher the stage of CKD, the more the patients with hypertension. High salt intake causes hypertension and results in kidney injury. Therefore, restriction of salt intake is a therapeutics for hypertension and CKD. Awareness of high salt intake by the CKD patient is the first step for treatment of hypertension. However, 24-hour (24-h) urinary collection is most reliable method for estimation of daily salt intake but cumbersome. Two equations for estimating 24-hour urinary sodium excretion from spot urine have been developed in Japanese general population but they have not been evaluated in CKD population. METHODS: The following equations were used for estimation of 24-h urinary Na excretion. Tanaka's equation: 24-h urinary Na excretion (mEq/day) = 21.98 x UNa/UCr x {-2.04 x age + 14.89 x weight (kg) + 16.14 x height (cm) -2244.45}^ 0.392 Kawasaki's equation: 24-h urinary Na excretion (mEq/day)=16.3x {(UNa/UCr)x 24h-UCr }^ 0.5 male:estimated 24h-UCr(mg/day)=15.1x BW + 7.4 x height - 12.4 x age - 80 female:estimated 24h-UCr(mg/day)=8.6 x BW + 5.1 x height - 4.7 x age - 75 We validated the equations by using urine samples of 24-h urinary collection and the first morning void in 136 patients with CKD who visited Nagoya University Hospital. RESULTS: Both equation were well estimated urinary creatinine excretion compared to measured UCr (Tanaka; r=0.670, p<0.01, Kawasaki; r=0.690, p<0.01). Bias, RMSE, accuracy within 30% of the estimated 24-h UNa by calculated both equations compared to measured 24-h UNa were shown. |
| نوع الوثيقة: | text |
| وصف الملف: | text/html |
| اللغة: | English |
| Relation: | http://ckj.oxfordjournals.org/cgi/content/short/4/suppl_2/4.s2.8; http://dx.doi.org/10.1093/ndtplus/4.s2.8 |
| DOI: | 10.1093/ndtplus/4.s2.8 |
| الاتاحة: | http://ckj.oxfordjournals.org/cgi/content/short/4/suppl_2/4.s2.8 https://doi.org/10.1093/ndtplus/4.s2.8 |
| Rights: | Copyright (C) 2011, European Renal Association - European Dialysis and Transplant Assoc |
| رقم الانضمام: | edsbas.C08E14D0 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/ndtplus/4.s2.8 |
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