Academic Journal

Oral Microbiota in Children with Cleft Lip and Palate: A Systematic Review

التفاصيل البيبلوغرافية
العنوان: Oral Microbiota in Children with Cleft Lip and Palate: A Systematic Review
المؤلفون: Jacek Świtała, Magdalena Sycińska-Dziarnowska, Gianrico Spagnuolo, Krzysztof Woźniak, Katarzyna Mańkowska, Liliana Szyszka-Sommerfeld
المصدر: Journal of Clinical Medicine ; Volume 12 ; Issue 18 ; Pages: 5867
بيانات النشر: Multidisciplinary Digital Publishing Institute
سنة النشر: 2023
المجموعة: MDPI Open Access Publishing
مصطلحات موضوعية: cleft lip and palate, congenital facial deformity, dental caries, oral health, oral microbiota, orthodontic treatment
الوصف: Background: Cleft in the lip and/or palate (CLP) is a congenital facial deformity that significantly impacts the oral cavity’s structure and function. This malformation can affect the oral microbiota. The objective of this systematic review was to examine and consolidate the current scientific evidence on the oral microflora in children with CLP. Methods: The search strategy included the PubMed, PubMed Central, Web of Science, Scopus, and Embase databases. The inclusion criteria were studies assessing oral microbiota in children with CLP. The Newcastle–Ottawa Scale (NOS) was used to evaluate the quality of the included studies. Results: The search strategy identified 422 potential articles. Twelve papers met the inclusion criteria. High heterogeneity was observed in methodologies, sample sites, and patient characteristics. Eight studies assessed the levels of Streptococcus mutans and Lactobacillus in saliva, with some reporting significantly higher levels in the cleft group compared to controls, while others found no differences. One study reported a significantly higher colonization rate of Candida species in patients with cleft lip and/or palate. Conclusion: The results of the available studies are unclear. Further research is needed to gain a comprehensive understanding of the oral microbiota and potential implications for oral health management in this population. The review was not registered Registration Statement.
نوع الوثيقة: text
وصف الملف: application/pdf
اللغة: English
Relation: https://dx.doi.org/10.3390/jcm12185867
DOI: 10.3390/jcm12185867
الاتاحة: https://doi.org/10.3390/jcm12185867
Rights: https://creativecommons.org/licenses/by/4.0/
رقم الانضمام: edsbas.C0719A29
قاعدة البيانات: BASE