Academic Journal
Review article Pharmacology of oleanolic acid and ursolic acid
| العنوان: | Review article Pharmacology of oleanolic acid and ursolic acid |
|---|---|
| المؤلفون: | Jie Liu |
| المساهمون: | The Pennsylvania State University CiteSeerX Archives |
| المصدر: | http://xa.yimg.com/kq/groups/15186538/1266142575/name/p+2+OA-1995.pdf. |
| المجموعة: | CiteSeerX |
| مصطلحات موضوعية: | Oleanolic acid, Ursolic acid, Triterpenoid, Hepatoprotection, Antiinflammatory, Antihyperlipidemia, Antitumor-promotion 1. introduction |
| الوصف: | Oleanolic acid and ursolic acid are triterpenoid compounds that exist widely in food, medicinal herbs and other plants. This review summarizes the pharmacological studies on these two triterpenoids. Both oleanolic acid and ursolic acid are effective in protecting against chemically induced liver injury in laboratory animals. Oleanolic acid has been marketed in China as an oral drug for human liver disorders. The mechanism of hepatoprotection by these two com-pounds may involve the inhibition of toxicant activation and the enhancement of the body defense systems. Oleanolic acid and ursolic acid have also been long-recognized to have antiinflammatory and antihyperlipidemic properties in laboratory animals, and more research is warranted to develop a therapy for patients. Recently, both compounds have been noted for their antitumor-promotion effects, which are stimulating additional research in this field. Oleanolic acid and ursolic acid are relatively non-toxic, and have been used in cosmetics and health products. The possible mechanisms for the pharmacological effects and the prospects for these two compounds are discussed. |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.470.5915; http://xa.yimg.com/kq/groups/15186538/1266142575/name/p+2+OA-1995.pdf |
| الاتاحة: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.470.5915 http://xa.yimg.com/kq/groups/15186538/1266142575/name/p+2+OA-1995.pdf |
| Rights: | Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: | edsbas.BFD7D6E1 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |